{
  "abstract": "Following an application from Lars Jansson, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Sweden, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to 'Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal'. Appethyl® is an aqueous extract from spinach leaves standardised by the manufacturing process and its lipase/colipase inhibition capacity in vitro. The Panel had evaluated the characterisation of Appethyl® in a previous opinion and as there were no changes made to the characterisation of Appethyl® in the current application, the Panel considers the food/constituent sufficiently characterised. The Panel notes that the claimed effect refers to changes in appetite ratings, which are not considered a beneficial physiological effect per se, and that no beneficial physiological effect resulting from changes in appetite ratings has been identified by the applicant. The Panel concludes that a cause-and-effect relationship between the consumption of Appethyl® and a beneficial physiological effect cannot be established in the context of this application.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 17,
  "authors": [
    {
      "name": "EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA)"
    },
    {
      "name": "Dominique Turck"
    },
    {
      "name": "Torsten Bohn",
      "orcid": "0000-0002-7825-0697"
    },
    {
      "name": "Montaña Cámara"
    },
    {
      "name": "Jacqueline Castenmiller"
    },
    {
      "name": "Stefaan de Henauw"
    },
    {
      "name": "Karen-Ildico Hirsch-Ernst"
    },
    {
      "name": "Angeles Jos"
    },
    {
      "name": "Alexandre Maciuk"
    },
    {
      "name": "Inge Mangelsdorf"
    },
    {
      "name": "Breige McNulty"
    },
    {
      "name": "Androniki Naska"
    },
    {
      "name": "Kristina Pentieva"
    },
    {
      "name": "Frank Thies"
    },
    {
      "name": "Ines Drenjančević"
    },
    {
      "name": "Thibault Fiolet"
    },
    {
      "name": "Alfonso Siani"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7q720a74sxkp1.bib",
  "cited_by": 0,
  "doi": "10.2903/j.efsa.2026.10384",
  "fulltext_url": "https://europepmc.org/articles/PMC13681248",
  "id": "7q720a74sxkp1",
  "issns": [
    "1831-4732"
  ],
  "landing_url": "https://europepmc.org/article/MED/42903356",
  "language": "eng",
  "licence": "CC-BY-ND",
  "licence_label": "CC BY-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2739|Consumer Attitudes and Food Labeling"
    ]
  ],
  "openalex": "W7223020625",
  "pdf_url": "https://europepmc.org/articles/PMC13681248?pdf=render",
  "pmcid": "PMC13681248",
  "pmid": "42903356",
  "published": "2026-10-20",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/7q720a74sxkp1.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42903356",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42903356"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2739|Consumer Attitudes and Food Labeling",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal: Evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.",
  "title_text": "Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal: Evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/7q720a74sxkp1",
  "venue": "EFSA journal. European Food Safety Authority",
  "versions": []
}