{
  "abstract": "Cervical cancer disproportionately affects socioeconomically disadvantaged populations in Ireland. HPV vaccination is central to Ireland’s cervical cancer elimination strategy. In the 2022/2023 academic year, the school-based immunisation programme introduced a single-dose HPV schedule to simplify delivery and improve uptake. The impact of this change, particularly in disadvantaged schools where attendance rates are poorer, has not been examined. This was a retrospective register-based cohort study using national aggregate school-level data. Vaccine uptake among first-year secondary school students in Ireland was examined across four academic years, spanning the transition from a two-dose to a single-dose schedule. Delivering Equality of Opportunity in Schools (DEIS) status was used as a proxy for socioeconomic status. Median uptake percentages were compared using non-parametric tests. Associations between school characteristics and uptake were examined using multivariable linear regression, while logistic regression assessed factors linked to achieving the ≥90% uptake target. A total of 2,918 school records were analysed, with about one-third classified as DEIS. Median HPV uptake increased after the single-dose introduction (80.1%) compared to the previous year (73.6%) but declined to 76.4% by 2024/2025. Uptake was consistently lower in DEIS schools. Few schools achieved the ≥90% target (14.6% in 2022/2023), with DEIS schools significantly less likely to do so. DEIS status was independently associated with lower uptake, while fee-paying and all-girls schools showed higher uptake. Following the introduction of the single-dose HPV vaccine schedule, there was a short-term increase in uptake, but this was not sustained. DEIS schools consistently demonstrated 13–15% lower uptake. These findings suggest that while a single-dose schedule may reduce logistical barriers, other factors continue to influence HPV uptake.\n\nKey messages: • Single-dose HPV vaccination led to a short-term rise in uptake, but gains were not sustained over time.\n\n• Disadvantaged schools have consistently lower uptake and are less likely to reach the ≥90% target, highlighting persistent socioeconomic inequalities.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "abstract",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "CM Sharkey"
    },
    {
      "name": "C White"
    },
    {
      "name": "L Marron"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7r1hcykpwyvw7.bib",
  "cited_by": 0,
  "doi": "10.1093/eurpub/ckag169.1895",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13699468/",
  "id": "7r1hcykpwyvw7",
  "issns": [
    "1101-1262",
    "1464-360X"
  ],
  "landing_url": "https://doi.org/10.1093/eurpub/ckag169.1895",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "6. Poster Displays"
    ],
    [
      "heading",
      "AcademicSubjects/MED00860"
    ],
    [
      "heading",
      "AcademicSubjects/SOC01210"
    ],
    [
      "heading",
      "AcademicSubjects/SOC02610"
    ],
    [
      "heading",
      "DV. Public health monitoring, reporting and foresight"
    ],
    [
      "openalex",
      "2713|Cervical Cancer and HPV Research"
    ]
  ],
  "openalex": "W7223684873",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13699468/pdf/?tool=EBI",
  "pmcid": "PMC13699468",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/7r1hcykpwyvw7.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:04Z",
      "native_id": "PMC13699468",
      "source": "pmc",
      "url": "https://doi.org/10.1093/eurpub/ckag169.1895"
    },
    {
      "first_seen": "2026-10-30T12:21:25Z",
      "native_id": "PMC:PMC13699468",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13699468"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Cervical Cancer and HPV Research",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Changing to a single-dose HPV vaccine schedule: impact on vaccine uptake and inequities in Ireland",
  "title_text": "Changing to a single-dose HPV vaccine schedule: impact on vaccine uptake and inequities in Ireland",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:36:02Z",
  "url": "https://research.draconitic.com/paper/7r1hcykpwyvw7",
  "venue": "The European Journal of Public Health",
  "versions": []
}