{
  "abstract": "We report the FeCl3-mediated direct addition of electron-rich arenes to the C2-position of electrophilic N-Ac indoles under mild conditions (room temperature, air). No functional group is required on the arene nucleophile: one of its C-H bonds is added to the C2[double bond, length as m-dash]C3 double bond of the indole nucleus in a Friedel-Crafts-type reaction. This dearomatisation process delivered a broad range of C2-arylated indolines.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "Raj Kumar Nandi"
    },
    {
      "name": "Friederike Ratsch"
    },
    {
      "name": "Rodolphe Beaud"
    },
    {
      "name": "Régis Guillot"
    },
    {
      "name": "Cyrille Kouklovsky"
    },
    {
      "name": "Guillaume Vincent"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7rce6dhtq47y5.bib",
  "cited_by": 42,
  "doi": "10.1039/c6cc01654e",
  "fulltext_url": null,
  "id": "7rce6dhtq47y5",
  "issns": [
    "1359-7345",
    "1364-548X"
  ],
  "landing_url": "https://hal.science/hal-05770958v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "openalex",
      "1605|Catalytic C–H Functionalization Methods"
    ]
  ],
  "openalex": "W2294693182",
  "pdf_url": "https://pubs.rsc.org/en/content/articlepdf/2016/cc/c6cc01654e",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-30",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/7rce6dhtq47y5.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:44Z",
      "native_id": "hal-05770958",
      "source": "hal",
      "url": "https://hal.science/hal-05770958v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Catalytic C–H Functionalization Methods",
      "subfield": "organic"
    }
  ],
  "title": "Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl 3",
  "title_text": "Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl 3",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:44Z",
  "url": "https://research.draconitic.com/paper/7rce6dhtq47y5",
  "venue": "Chemical Communications",
  "versions": []
}