{
  "abstract": "Background: Given the poor prognosis and marked geographic and socioeconomic inequalities in the burden of genitourinary cancers, updating the global epidemiological landscape is essential for informing region-specific and equity-oriented strategies.\n\nMethods: Using GLOBOCAN 2024, we estimated age-standardized incidence (ASIR), mortality (ASMR), and 1−mortality-to-incidence ratio (1−M/I) for genitourinary cancers. Socioeconomic inequalities across Human Development Index (HDI) levels were quantified using the slope index of inequality (SII) and concentration index (ConI). We further decomposed factors contributing to these inequalities and estimated population attributable fractions (PAFs) for selected modifiable risk factors under specified counterfactual scenarios.\n\nResults: In 2024, the global ASIR and ASMR of genitourinary cancers were 35.97 and 9.85 per 100,000, respectively, with a 1−M/I of 0.73. ASIRs were the highest in Northern America, Europe, and Australasia, whereas ASMRs peaked in Caribbean and African regions. ASIR and 1−M/I were substantially higher in very-high-HDI than low-HDI countries (ASIR: 71.07 vs 25.72 per 100,000; 1−M/I: 0.82 vs 0.40 per 100,000). Significant inequalities were observed for ASIR (SII: 62.15; ConI: 0.24) and 1−M/I (SII: 0.51; ConI: 0.14). Education, income, universal health coverage, and health expenditure were major contributors. Globally, Particulate Matter 2.5 showed the largest estimated PAFs for kidney (24.09%–28.53%) and bladder cancers (20.86%–24.52%) under alternative counterfactual exposure levels. The HIV-associated PAF for penile cancer was 2.82% globally and 10.64% in low-HDI countries, indicating marked heterogeneity across cancer types and HDI levels.\n\nConclusions: Genitourinary cancers exhibit geographic and socioeconomic inequalities, with pronounced heterogeneity in potentially attributable burden across modifiable risk factors and HDI levels. These findings support context-specific prevention and health-system strategies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Key Laboratory of Epidemiology of Major Diseases, Ministry of Education, Beijing, China",
    "National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China",
    "School of Health Humanities, Peking University, Beijing, China",
    "NHMRC Clinical Trials Centre, The University of Sydney, Sydney, Australia",
    "Senior Department of Urology, Third Medical Center of PLA General Hospital, Beijing, China",
    "Department of Urology, Beijing Hospital, National Center of Gerontology, Beijing, China",
    "Institute for Artificial Intelligence, Peking University, Beijing, China",
    "Beijing Key Laboratory of Human Microbiome Precision Medicine and Microbial Agent Development, Beijing, China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yuhao Li"
    },
    {
      "affs": [
        0
      ],
      "name": "Yile You"
    },
    {
      "affs": [
        1
      ],
      "name": "Dequan Shi"
    },
    {
      "affs": [
        2
      ],
      "name": "Yiqiao Lv"
    },
    {
      "affs": [
        3
      ],
      "name": "Xin Zhan"
    },
    {
      "affs": [
        0
      ],
      "name": "Jieying Chen"
    },
    {
      "affs": [
        4
      ],
      "name": "Qing Yuan"
    },
    {
      "affs": [
        5
      ],
      "name": "Ming Liu"
    },
    {
      "affs": [
        1
      ],
      "name": "Ru Chen"
    },
    {
      "affs": [
        0,
        6,
        7
      ],
      "name": "Shengfeng Wang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7th35r8t616p3.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jncc.2026.09.009",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13731794/",
  "id": "7th35r8t616p3",
  "issns": [
    "2096-8663",
    "2667-0054"
  ],
  "landing_url": "https://doi.org/10.1016/j.jncc.2026.09.009",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Full Length Article"
    ],
    [
      "openalex",
      "2730|Global Cancer Incidence and Screening"
    ]
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  "openalex": "W7214897218",
  "pdf_url": "https://www.sciencedirect.com/science/article/pii/S2667005426001274/pdf",
  "pmcid": "PMC13731794",
  "pmid": "42985077",
  "published": "2026-09-30",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/7th35r8t616p3.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:21:55Z",
      "native_id": "PMC13731794",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.jncc.2026.09.009"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Global Cancer Incidence and Screening",
      "subfield": "oncology"
    }
  ],
  "title": "Socioeconomic inequalities in the epidemiological landscape of genitourinary cancers: a GLOBOCAN 2024 analysis",
  "title_text": "Socioeconomic inequalities in the epidemiological landscape of genitourinary cancers: a GLOBOCAN 2024 analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:55Z",
  "url": "https://research.draconitic.com/paper/7th35r8t616p3",
  "venue": "Journal of the National Cancer Center",
  "versions": []
}