{
  "abstract": "Background\n\nLocal antibiotics are increasingly used in the management of fracture-related infection (FRI), but international practice patterns regarding their indications, antibiotic selection, and application methods remain heterogeneous and insufficiently standardised.Methods\n\nAn international survey was conducted among members of the Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT). The web-based questionnaire included 16 items on indications, antibiotic selection, and application methods. Participation was voluntary and self-selected. Responses were analysed descriptively, with regional stratification performed for exploratory purposes. Of 118 started questionnaires, 87 were included in the analysis (73.7%); the overall response rate could not be calculated because the total number of invited SICOT members was unavailable.Results\n\n87 surgeons from six continents participated, most with extensive clinical experience. The analysis revealed substantial heterogeneity in the frequency of local antibiotic use as well as in the selected antibiotic agents and application methods. An increase in local antibiotic use over the past decade was reported by 48/87 (55.2%) respondents. The main reported reasons for using local antibiotics were surgeon's preference (44/87, 50.6%) and intraoperative findings (26/87, 29.9%).Conclusions\n\nAmong the surveyed SICOT respondents, local antibiotic use was reported across all represented regions, but substantial variation was observed in reported indications, antibiotic selection, and delivery methods. Given the unavailable invitation denominator and highly imbalanced regional sample sizes, these findings should be interpreted as exploratory and should not be considered evidence of treatment effectiveness or preferred practice.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Trauma Surgery, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.",
    "Department of Traumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.",
    "Department of Trauma and Orthopaedic Surgery, BG Klinikum Unfallkrankenhaus Berlin, Berlin, Germany.",
    "Lehrstuhl für Traumatologie, Charité - Universitätsmedizin Berlin, CharitéCentrum für Orthopädie und Unfallchirurgie CC 9, Berlin, Germany.",
    "Department of Orthopaedics and Trauma-Surgery, University Hospital Vienna, Medical University of Vienna, Vienna, Austria.",
    "Pediatric Orthopaedics and Trauma, Al Jalila Children's Speciality Hospital, Dubai, UAE.",
    "NSH and NMH, Narayana Health Group of Hospitals, Kolkata, India.",
    "Department of Trauma Surgery, Diakonie Klinikum Landkreis Schwäbisch Hall, Schwäbisch Hall, Germany.",
    "Department of Trauma Surgery, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany. Marc.Hanschen@mri.tum.de."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 15,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Gregor Bielesch"
    },
    {
      "affs": [
        0
      ],
      "name": "Conrad Ketzer"
    },
    {
      "affs": [
        0
      ],
      "name": "Ahmed Ellafi"
    },
    {
      "affs": [
        0
      ],
      "name": "Olivia Bohe"
    },
    {
      "affs": [
        0
      ],
      "name": "Peter Biberthaler"
    },
    {
      "affs": [
        0
      ],
      "name": "Philipp Rittstieg"
    },
    {
      "affs": [
        1
      ],
      "name": "Felix Karl-Ludwig Klingebiel"
    },
    {
      "affs": [
        1
      ],
      "name": "Roman Pfeifer"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Georg Osterhoff"
    },
    {
      "affs": [
        4
      ],
      "name": "Stephan Frenzel"
    },
    {
      "affs": [
        5
      ],
      "name": "Sattar Alshryda"
    },
    {
      "affs": [
        6
      ],
      "name": "Arindam Banerjee"
    },
    {
      "affs": [
        0,
        7
      ],
      "name": "Stefan Huber-Wagner"
    },
    {
      "affs": [
        8
      ],
      "name": "Marc Hanschen"
    },
    {
      "name": "SICOT Global Research Network"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7vd38j463rrcg.bib",
  "cited_by": 0,
  "doi": "10.1186/s12891-026-10585-7",
  "fulltext_url": "https://europepmc.org/articles/PMC13670668",
  "id": "7vd38j463rrcg",
  "issns": [
    "1471-2474"
  ],
  "landing_url": "https://europepmc.org/article/MED/42875762",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Orthopedic Infections and Treatments"
    ]
  ],
  "openalex": "W7221096148",
  "pdf_url": "https://europepmc.org/articles/PMC13670668?pdf=render",
  "pmcid": "PMC13670668",
  "pmid": "42875762",
  "published": "2026-10-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/7vd38j463rrcg.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:00Z",
      "native_id": "MED:42875762",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42875762"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Orthopedic Infections and Treatments",
      "subfield": "surgery"
    }
  ],
  "title": "Reported practice patterns in the use of local antibiotics for fracture-related infection among SICOT respondents: an international survey.",
  "title_text": "Reported practice patterns in the use of local antibiotics for fracture-related infection among SICOT respondents: an international survey.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:00Z",
  "url": "https://research.draconitic.com/paper/7vd38j463rrcg",
  "venue": "BMC musculoskeletal disorders",
  "versions": []
}