{ "abstract": "Background\n\nElectronic patient-reported outcome (ePRO) systems support symptom monitoring after chemotherapy; however, their integration into structured nurse-led oncology workflows remains limited. In this study, we aimed to develop and evaluate the short-term feasibility and usability of a nurse-led ePRO system for home-based postchemotherapy symptom monitoring and structured nursing triage for cancer patients.Methods\n\nThis single-arm feasibility study was conducted at a cancer center in Taiwan between April and September 2024 among adult patients requiring home-based symptom monitoring after hospital-based chemotherapy care. The nurse-led digital system was designed to support weekly self-reporting of 12 chemotherapy-related symptoms using the Chemotherapy Toxicity Self-Assessment Questionnaire. The system incorporated rule-based triage categorization using green, orange, and red risk levels and predefined nurse response protocols. Feasibility outcomes included report adherence, triage alert management, and system performance. Usability was evaluated using the System Usability Scale.Results\n\nForty-two patients submitted 306 symptom reports during the 8-week monitoring period, corresponding to an overall adherence rate of 91.1%. Among all reports, 16.3% generated orange alerts requiring nurse follow-up and 6.5% generated red alerts requiring urgent review. Fatigue, pain, and hand-foot syndrome were the most frequently reported abnormal symptoms. All orange and red alerts had documented nursing review. The system met the predefined technical performance indicators during simulated load testing, and achieved a mean System Usability Scale score of 92.6 ± 6.46.Conclusions\n\nThis nurse-led ePRO system demonstrated favorable short-term feasibility and usability for home-based postchemotherapy symptom monitoring and structured nursing triage. These findings support the practicality of integrating structured ePRO monitoring into postchemotherapy nursing care. Further multicenter and comparative studies are warranted to evaluate long-term engagement, scalability, and clinical outcomes.", "abstract_shown": true, "affiliations": [ "Graduate Institute of Medical Sciences, College of Medicine, National Defense Medical University, Taipei City, Taiwan.", "Department of Nursing, National Taiwan University Cancer Center, Taipei City, Taiwan.", "Department of Oncology, National Taiwan University Hospital, Taipei City, Taiwan.", "Department of Medical Oncology, National Taiwan University Cancer Center, Taipei City, Taiwan.", "Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei City, Taiwan.", "Department of Computer Science and Information Engineering, National Taiwan University of Science and Technology, Taipei City, Taiwan.", "College of Public Health, National Defense Medical University, Taipei City, Taiwan.", "Big Data Research Center, College of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.", "Department of Healthcare Administration and Medical Informatics, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.", "Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical University, Taipei City, Taiwan.", "Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, National Defense Medical University, Taipei City, Taiwan.", "Department of Nursing, Tri-Service General Hospital, National Defense Medical University, Taipei City, Taiwan.", "College of Nursing, National Defense Medical University, Taipei City, Taiwan." ], "article_type": "research article", "arxiv": null, "author_total": 7, "authors": [ { "affs": [ 0, 1 ], "name": "Chiao-Chi Kuan", "orcid": "0000-0001-6506-2761" }, { "affs": [ 2, 3, 4 ], "name": "Jhe-Cyuan Guo", "orcid": "0000-0002-6689-9640" }, { "affs": [ 5 ], "name": "Shan-Hsiang Shen", "orcid": "0000-0002-2865-6760" }, { "affs": [ 2, 3, 4 ], "name": "Chiun Hsu", "orcid": "0000-0002-1122-0055" }, { "affs": [ 6, 7, 8 ], "name": "Chi-Ming Chu", "orcid": "0000-0001-8563-1378" }, { "affs": [ 9, 10 ], "name": "Chi-Kang Lin", "orcid": "0000-0001-8608-1320" }, { "affs": [ 0, 11, 12 ], "name": "Hsueh-Hsing Pan", "orcid": "0000-0002-9020-3279" } ], "bibtex": "https://research.draconitic.com/paper/7x8hpzz98k08d.bib", "cited_by": 0, "doi": "10.1002/cam4.72377", "fulltext_url": "https://europepmc.org/articles/PMC13688432", "id": "7x8hpzz98k08d", "issns": [ "2045-7634" ], "landing_url": "https://europepmc.org/article/MED/42910562", "language": "eng", "licence": "CC-BY-NC", "licence_label": "CC BY-NC", "licence_source": "article", "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/", "metadata_licence": null, "native_subjects": [ [ "openalex", "2730|Cancer survivorship and care" ] ], "openalex": "W7223169872", "pdf_url": "https://europepmc.org/articles/PMC13688432?pdf=render", "pmcid": "PMC13688432", "pmid": "42910562", "published": "2026-10-01", "publisher": null, "ris": "https://research.draconitic.com/paper/7x8hpzz98k08d.ris", "sources": [ { "first_seen": "2026-10-30T12:20:14Z", "native_id": "MED:42910562", "source": "europepmc", "url": "https://europepmc.org/article/MED/42910562" } ], "subjects": [ { "field": "medicine", "origin": "openalex:2730|Cancer survivorship and care", "subfield": "oncology" } ], "title": "Development and Feasibility Evaluation of a Nurse-Led ePRO System for Home-Based Post-Chemotherapy Symptom Management in Patients With Cancer.", "title_text": "Development and Feasibility Evaluation of a Nurse-Led ePRO System for Home-Based Post-Chemotherapy Symptom Management in Patients With Cancer.", "type": "peer-reviewed", "updated_at": "2026-10-30T12:20:14Z", "url": "https://research.draconitic.com/paper/7x8hpzz98k08d", "venue": "Cancer medicine", "versions": [] }