{
  "abstract": "Introduction\n\nIn the modern poultry industry, nanoencapsulation protects natural antioxidants like epicatechin from harsh conditions, boosting their effectiveness.Methods\n\nIn this study, broilers were fed four diets with 0, 75, 150, and 300 mg/kg niosomal epicatechin (Nio/Epicatechin) to evaluate its boosted effects on performance, immunity, meat quality, antioxidant stability, and lipid peroxidation during frozen storage.Results and discussion\n\nThe highest dose (300 mg/kg) produced the best results: chickens grew faster, converted feed more efficiently, and had higher carcass yields. Muscle growth genes (MyoD, mTOR, MyoG) were turned on, while the growth-limiting gene MSTN was suppressed. Meat quality improved, with lower drip, thaw, and cooking losses, and better pH stability. Profits increased, and feed costs dropped. Fat and cholesterol in breast and thigh meat were significantly reduced, as fat-making genes (FAS and ACC) were downregulated. After 90 days of frozen storage, meat from the 300 mg/kg group had higher antioxidant capacity, more phenolics and flavonoids, and lower levels of harmful oxidation products like malondialdehyde and cholesterol oxides. Antioxidant enzyme genes (SOD-1, catalase, GSH-Px, NQO1, HO-1) were more active, and the meat showed stronger free radical scavenging power. Overall, Nio/Epicatechin supplementation, especially at 300 mg/kg, enhances growth, improves meat nutritional quality, boosts oxidative stability during frozen storage, and extends shelf life, making it a valuable strategy for poultry production.",
  "abstract_shown": true,
  "affiliations": [
    "Environment and Life Sciences Research Center, Kuwait Institute for Scientific Research, Safat, Kuwait.",
    "Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.",
    "Department of Animal Wealth Development, Veterinary Economics and Farm Management, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.",
    "Food Hygiene Department, Animal Health Research Institute (AHRI), Mansoura Branch, Agriculture Research Center (ARC), Giza, Egypt.",
    "Department of Biotechnology, Reference Laboratory for Quality Control of Poultry Production (RLQP), Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Zagazig, Egypt.",
    "Biochemistry Department, Animal Health Research Institute (AHRI), Mansoura Branch, Agriculture Research Center (ARC), Giza, Egypt.",
    "Department of Biochemistry, Animal Health Research Institute (AHRI), Mansoura Branch, Agriculture Research Center (ARC), Giza, Egypt.",
    "Agricultural Research Center, Department of Food Hygiene, Food Inspection Laboratory Damietta Port, Animal Health Research Institute, Damietta, Egypt.",
    "Department of Nutrition, Oncology Center Faculty of Medicine Mansoura University, Mansoura, Egypt.",
    "Department of Toxicology and Biochemical, Zagazig Branch Animal Health Research Institute (AHRI) Agricultural Research Centre (ARC), Zagazig, Egypt.",
    "Department of Biochemistry, Animal Health Research Institute, Zagazig Branch, Agriculture Research Center, Zagazig, Egypt.",
    "Department of Biotechnology, Agriculture Research Center (ARC), Animal Health Research Institute (AHRI), Giza, Egypt.",
    "Department of Public Health, College of Veterinary Medicine, King Faisal University, Al Hofuf, Al Ahsa, Saudi Arabia.",
    "Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
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        0
      ],
      "name": "H S Al-Khalaifah"
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    {
      "affs": [
        1
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      "name": "Marwa I Abd El-Hamid"
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    {
      "affs": [
        2
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      "name": "Sara E Shahin"
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    {
      "affs": [
        3
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      "name": "Aya M Emam"
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    {
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        4
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      "name": "Amal S A El Oksh"
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    {
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        5
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      "name": "Marwa Samir"
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    {
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        6
      ],
      "name": "Nour El-Hoda Khayrat Hammad"
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      "name": "Samah A M Abou Shehatta"
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        8
      ],
      "name": "Elham Elsayed Abo-Almagd"
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    {
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        9
      ],
      "name": "Dalia W A H Elged"
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    {
      "affs": [
        10
      ],
      "name": "Dalia Ibrahim Mohamed"
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        11
      ],
      "name": "Wessam Youssef"
    },
    {
      "affs": [
        12
      ],
      "name": "Sherief M Abdel-Raheem"
    },
    {
      "affs": [
        13
      ],
      "name": "Doaa Ibrahim"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7y4pa9zank7gr.bib",
  "cited_by": 0,
  "doi": "10.3389/fvets.2026.1960674",
  "fulltext_url": "https://europepmc.org/articles/PMC13711052",
  "id": "7y4pa9zank7gr",
  "issns": [
    "2297-1769"
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  "landing_url": "https://europepmc.org/article/MED/42948345",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
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      "1103|Meat and Animal Product Quality"
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  "pdf_url": "https://europepmc.org/articles/PMC13711052?pdf=render",
  "pmcid": "PMC13711052",
  "pmid": "42948345",
  "published": "2026-10-13",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/7y4pa9zank7gr.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:34Z",
      "native_id": "MED:42948345",
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    {
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      "native_id": "PMC13711052",
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      "url": "https://doi.org/10.3389/fvets.2026.1960674"
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  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1103|Meat and Animal Product Quality",
      "subfield": "zoology-behaviour"
    }
  ],
  "title": "Mechanistic insights into niosomal epicatechin on nutritional value and functional quality of chicken meat and economics: monitoring color and oxidative stability for extended shelf life during frozen storage.",
  "title_text": "Mechanistic insights into niosomal epicatechin on nutritional value and functional quality of chicken meat and economics: monitoring color and oxidative stability for extended shelf life during frozen storage.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:54Z",
  "url": "https://research.draconitic.com/paper/7y4pa9zank7gr",
  "venue": "Frontiers in veterinary science",
  "versions": []
}