{
  "abstract": "Urban zones are rapidly expanding worldwide, exposing organisms to complex and multidimensional stressors. However, linking organismal responses to environmental change at ecologically relevant scales remains a major challenge. To investigate the constraints imposed on fish living in coastal urban environments, we apply a landscape-scale framework to identify molecular signatures associated with human activities. Using transcriptomes from a common coral reef fish, Chrysiptera cyanea , sampled across 18 coastal sites in Okinawa, Japan, we implement scalable analytical and visualisation tools and identify coordinated shifts in metabolic, immune, and inflammatory pathways. By integrating field data with a fasting-feeding experiment, we find that transcriptomes of adult fish from urbanised sites resemble those of well-fed experimental fish, suggesting that these areas provide an energy-rich diet while imposing chronic stress. Our findings reveal how anthropogenic activities reshape organismal resilience and demonstrate the power of landscape transcriptomics as a link between molecular signatures and ecological outcomes across changing environments.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "Emma Gairin",
      "orcid": "0000-0001-6898-8084"
    },
    {
      "name": "Saori Miura"
    },
    {
      "name": "Zoé Chamot",
      "orcid": "0000-0002-6316-1309"
    },
    {
      "name": "Camille A. Sautereau"
    },
    {
      "name": "Jann Zwahlen"
    },
    {
      "name": "Hiroki Takamiyagi"
    },
    {
      "name": "Yann Gibert"
    },
    {
      "name": "Marcela Herrera",
      "orcid": "0000-0001-6021-3989"
    },
    {
      "name": "Vincent Laudet",
      "orcid": "0000-0003-4022-4175"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7yrgg2vhjxahr.bib",
  "cited_by": 0,
  "doi": "10.1038/s41467-026-77751-2",
  "fulltext_url": null,
  "id": "7yrgg2vhjxahr",
  "issns": [
    "2041-1723"
  ],
  "landing_url": "https://www.nature.com/articles/s41467-026-77751-2",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2303|Coral and Marine Ecosystems Studies"
    ]
  ],
  "openalex": "W7221067684",
  "pdf_url": "https://www.nature.com/articles/s41467-026-77751-2.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-09",
  "publisher": "Springer Science and Business Media LLC",
  "ris": "https://research.draconitic.com/paper/7yrgg2vhjxahr.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:38Z",
      "native_id": "10.1038/s41467-026-77751-2",
      "source": "crossref",
      "url": "https://www.nature.com/articles/s41467-026-77751-2"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2303|Coral and Marine Ecosystems Studies",
      "subfield": "ecology"
    }
  ],
  "title": "Landscape transcriptomics reveals ecological constraints on fish under anthropogenic coastal change",
  "title_text": "Landscape transcriptomics reveals ecological constraints on fish under anthropogenic coastal change",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:38Z",
  "url": "https://research.draconitic.com/paper/7yrgg2vhjxahr",
  "venue": "Nature Communications",
  "versions": []
}