{
  "abstract": "Objective. To assess the impact of comorbidity on the diagnostic value of complete blood count parameters in patients with acute small bowel obstruction.\n\nMaterials and methods. A single-centre retrospective cohort study included 130 patients who underwent surgery for acute small bowel obstruction. Complete blood count parameters were analysed in the overall cohort (n = 130), in patients with comorbidities (n = 96) and in patients without comorbidities (n = 34). Standard comparison methods, ROC analysis with calculation of the area under the ROC curve, and regression models were used for statistical analysis.\n\nResults. Complete blood count parameters were higher in patients with complicated acute small bowel obstruction; however, there were no significant differences in these parameters between the overall cohort and patients with comorbidities. Only the absolute neutrophil count differed significantly (Z = 1.968; p = 0.049) in patients without comorbidities. The optimal cut-off values and diagnostic accuracy of the complete blood count parameters varied depending on the presence of comorbidities. In the overall cohort and in patients with comorbidities, the area under the ROC curve approached the level of random discrimination (0.53–0.59). In patients without comorbidities, the neutrophil count demonstrated the highest diagnostic value (area under the ROC curve = 0.73; 95% confidence interval 0.56–0.90). In the regression model, the Charlson comorbidity index had the most consistent effect on changes in the Charlson score. The clinical presentation of acute small bowel obstruction independently influenced only the neutrophil count.\n\nConclusions. The prognostic value of complete blood count parameters for distinguishing complications of small bowel obstruction is influenced by the presence of comorbidity, which may limit their universal application. In patients with comorbidities, none of the parameters showed significant differences. Only the absolute neutrophil count demonstrated clinically relevant differences in patients without comorbidities.",
  "abstract_shown": true,
  "affiliations": [
    "Bukovina State Medical University, Chernivtsi"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "F. V. Grynchuk",
      "orcid": "0000-0002-7482-442X"
    },
    {
      "affs": [
        0
      ],
      "name": "V. V. Hordit",
      "orcid": "0009-0003-0125-5435"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/817wdgzyhm6nf.bib",
  "cited_by": 0,
  "doi": "10.26779/2786-832x.2026.5.11",
  "fulltext_url": "https://hirurgiya.com.ua/index.php/journal/article/view/1357",
  "id": "817wdgzyhm6nf",
  "issns": [
    "2786-832X",
    "2786-8311"
  ],
  "landing_url": "https://doi.org/10.26779/2786-832x.2026.5.11",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RD1-811"
    ],
    [
      "openalex",
      "2746|Intestinal and Peritoneal Adhesions"
    ]
  ],
  "openalex": "W7223298004",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Liga-Inform ltd.",
  "ris": "https://research.draconitic.com/paper/817wdgzyhm6nf.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:02Z",
      "native_id": "eb09eb68884f40be9af99f12a5043398",
      "source": "doaj",
      "url": "https://doi.org/10.26779/2786-832x.2026.5.11"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Intestinal and Peritoneal Adhesions",
      "subfield": "surgery"
    }
  ],
  "title": "The impact of comorbidity on the diagnostic value of complete blood count parameters in acute small bowel obstruction",
  "title_text": "The impact of comorbidity on the diagnostic value of complete blood count parameters in acute small bowel obstruction",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:44:02Z",
  "url": "https://research.draconitic.com/paper/817wdgzyhm6nf",
  "venue": "Український журнал клінічної хірургії",
  "versions": []
}