{
  "abstract": "Tryptophan (Trp), an essential amino acid, plays a central role in metabolism, inflammation, immunity, and energy homeostasis. It is primarily metabolized through the kynurenine, indole, and serotonin pathways, generating metabolites with either protective or harmful effects depending on the physiological and tissue context. Dysregulation of these pathways contributes to obesity, diabetes, and cardiovascular diseases. Understanding these mechanisms paves the way for personalized nutritional and therapeutic strategies to prevent and manage cardiometabolic diseases.",
  "abstract_shown": true,
  "affiliations": [
    "Université Paris Cité, Inserm U970, Centre de recherche cardiovasculaire (PARCC), Hôpital européen Georges Pompidou"
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  "article_type": "review",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
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      ],
      "name": "Mouna Chajadine"
    },
    {
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        0
      ],
      "name": "Ludivine Laurans",
      "orcid": "0009-0003-2296-5153"
    },
    {
      "affs": [
        0
      ],
      "name": "Soraya Taleb",
      "orcid": "0000-0002-6650-619X"
    }
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  "bibtex": "https://research.draconitic.com/paper/81djxym4j4f76.bib",
  "cited_by": 12,
  "doi": "10.1051/medsci/2026094",
  "fulltext_url": null,
  "id": "81djxym4j4f76",
  "issns": [
    "0767-0974",
    "1958-5381"
  ],
  "landing_url": "https://doi.org/10.1051/medsci/2026094",
  "language": "fr",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2803|Tryptophan and brain disorders"
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  "pdf_url": "https://www.medecinesciences.org/articles/medsci/pdf/2026/06/medsci20250184.pdf",
  "pmcid": null,
  "pmid": "42466688",
  "published": "2026-06-01",
  "publisher": "EDP Sciences",
  "ris": "https://research.draconitic.com/paper/81djxym4j4f76.ris",
  "sources": [
    {
      "first_seen": "2026-11-05T13:21:01Z",
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      "url": "https://doi.org/10.1051/medsci/2026094"
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2803|Tryptophan and brain disorders",
      "subfield": "psychiatry"
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  ],
  "title": "Le métabolisme du tryptophane : un acteur clé des maladies cardiométaboliques",
  "title_text": "Le métabolisme du tryptophane : un acteur clé des maladies cardiométaboliques",
  "type": "peer-reviewed",
  "updated_at": "2026-11-12T13:20:46Z",
  "url": "https://research.draconitic.com/paper/81djxym4j4f76",
  "venue": "médecine/sciences",
  "versions": []
}