{
  "abstract": "The insect central complex governs intricate navigational behaviors. One key region of the central complex, the fan-shaped body (FB), is where movement decisions are computed during goal-directed behaviors. However, our knowledge of when FB circuits are deployed is limited, and the FB has only been directly implicated in a few, narrowly defined behaviors. Here, we demonstrate that FB circuits affect course-correcting movements that, over long timescales, align the fly's heading with the perceived direction of optic flow. Silencing a major input neuronal population to the FB, the PFN d neurons, abolishes this behavior while leaving certain reflexive turning behaviors intact. Further, introduction of a fictive error signal in either the PFN d or PFN a neurons via optogenetic activation reveals that they are sufficient to affect the forward movement of the fly while slightly biasing its heading direction. We propose a model whereby the fly recruits the circuitry of the central complex to selectively influence features of movement that emerge over long timescales.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Neuroscience, Brown University, Providence, RI 02912, USA",
    "Carney Institute for Brain Science, Brown University, Providence, RI 02912, USA",
    "Current Address: Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08540, USA",
    "Current Address: Weill Cornell Medical College, New York, NY, 10065, USA",
    "Current Address: Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Anthony M Crown"
    },
    {
      "affs": [
        0,
        1,
        3
      ],
      "name": "Annie H Wu"
    },
    {
      "affs": [
        0,
        1,
        4
      ],
      "name": "Lindsey Hofflander"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Gilad Barnea"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/835j2sh0j77va.bib",
  "cited_by": 0,
  "doi": "10.1016/j.cub.2026.09.069",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13718720/",
  "id": "835j2sh0j77va",
  "issns": [
    "0960-9822",
    "1879-0445"
  ],
  "landing_url": "https://doi.org/10.1016/j.cub.2026.09.069",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "2804|Neurobiology and Insect Physiology Research"
    ]
  ],
  "openalex": "W7223212064",
  "pdf_url": null,
  "pmcid": "PMC13718720",
  "pmid": "42913650",
  "published": "2026-10-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/835j2sh0j77va.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T12:22:41Z",
      "native_id": "PMC13718720",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.cub.2026.09.069"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2804|Neurobiology and Insect Physiology Research",
      "subfield": "neuroscience"
    }
  ],
  "title": "Selective control of course correction over long timescales in the Drosophila central complex",
  "title_text": "Selective control of course correction over long timescales in the Drosophila central complex",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:22:41Z",
  "url": "https://research.draconitic.com/paper/835j2sh0j77va",
  "venue": "Current biology : CB",
  "versions": []
}