{
  "abstract": "We report a mechanochemical copper-catalyzed deoxygenative amination of alcohols via O-alkylisourea intermediates under ball-milling. This one-pot method accelerates conversion, tolerates primary, secondary, and challenging tertiary alcohols, and enables late-stage functionalization and scalable drug synthesis, providing a versatile C(sp3)–N bond-forming platform.",
  "abstract_shown": true,
  "affiliations": [
    "aState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry, Nanjing University, Nanjing 210023, China.",
    "aState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry, Nanjing University, Nanjing 210023, China.bAnHui Technology Research Center of Optoelectronic Technology Appliance, Biomimetic Energy Laboratory, School of Electrical Engineering, Tongling University, Tongling 244000, China."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
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        0
      ],
      "name": "Yuntian Shi"
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    {
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        0
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      "name": "Wangzhe Chen"
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    {
      "affs": [
        0
      ],
      "name": "Jing Liu"
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    {
      "affs": [
        0
      ],
      "name": "Zhen Wang"
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    {
      "affs": [
        0
      ],
      "name": "Xian Zhang"
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    {
      "affs": [
        0
      ],
      "name": "Heyin Li"
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    {
      "affs": [
        0
      ],
      "name": "Chao Sun"
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    {
      "affs": [
        0
      ],
      "name": "Chen Xing"
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    {
      "affs": [
        1
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      "name": "Zhenlei Zou"
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    {
      "affs": [
        0
      ],
      "name": "Weigang Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Yi Wang",
      "orcid": "0000-0002-8700-7621"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/83dnfyhge8nnv.bib",
  "cited_by": 0,
  "doi": "10.1039/d6mr00094k",
  "fulltext_url": "https://pubs.rsc.org/mr/article-pdf/3/6/892/14866860/d6mr00094k.pdf",
  "id": "83dnfyhge8nnv",
  "issns": [
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  "landing_url": "https://doi.org/10.1039/d6mr00094k",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
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      "lcc",
      "QD1-999"
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      "openalex",
      "1605|Synthesis and Catalytic Reactions"
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  "openalex": "W7221149168",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "The Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/83dnfyhge8nnv.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T14:21:36Z",
      "native_id": "0c7fcbb7c9604b5da943a7adb8220f1a",
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      "url": "https://doi.org/10.1039/d6mr00094k"
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  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Synthesis and Catalytic Reactions",
      "subfield": "organic"
    }
  ],
  "title": "Mechanochemistry-promoted Cu-catalyzed deoxygenative amination of O-alkylisourea",
  "title_text": "Mechanochemistry-promoted Cu-catalyzed deoxygenative amination of O-alkylisourea",
  "type": "peer-reviewed",
  "updated_at": "2026-11-05T14:20:33Z",
  "url": "https://research.draconitic.com/paper/83dnfyhge8nnv",
  "venue": "RSC Mechanochemistry",
  "versions": []
}