{
  "abstract": "BackgroundComparing long-term outcomes of gastric cancer surgery between hospitals requires a common reference. Risk-adjusted benchmarks depend on the model and population used to build them and are difficult for another hospital to reproduce. TNM stage is a prognostic classification already recorded for every resected gastric cancer. We report unadjusted stage-specific overall survival from a consecutive cohort with complete follow-up as reference data and propose a minimal dataset for producing comparable figures elsewhere.\n\nMethodsThe cohort comprised 690 consecutive eligible patients who underwent curative-intent D2 gastrectomy for stage I to III adenocarcinoma at Ruijin Hospital, Shanghai, in 2019. All operations were performed by eight experienced, high-volume consultant surgeons. Stage followed the AJCC 8th edition: pTNM after upfront surgery (n = 570) and ypTNM after neoadjuvant chemotherapy (n = 120). Overall survival was estimated by the Kaplan-Meier method without adjustment.\n\nResultsThere were 199 deaths, 181 within five years. Every survivor was followed for at least 68.1 months. After upfront surgery, five-year overall survival was 95.0% (95% CI 91.4 to 97.1) for stage I, 83.8% (76.5 to 89.0) for stage II and 56.5% (49.2 to 63.1) for stage III, and was 95.0% in IA and 95.2% in IB, falling to 26.7% in IIIC. After neoadjuvant chemotherapy, five-year survival was 78.6%, 61.9% and 31.3% for ypStage I, II and III. Pooling pTNM and ypTNM lowered stage III five-year survival to 50.2%. The proposed minimal dataset has 16 items, 13 of them recorded during the admission for gastrectomy.\n\nConclusionsThese figures are intended as a reference for comparing hospitals rather than as a standard of care. We propose 16 items, most of them routinely recorded, from which another hospital can produce the same table and compare its results by stage.",
  "abstract_shown": true,
  "affiliations": [
    "Department of General Surgery, Gastrointestinal Surgery Unit, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Gast"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "B. K. Sah"
    },
    {
      "name": "D. Gu"
    },
    {
      "name": "J. Li"
    },
    {
      "name": "E. Chen"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/83g47pt4c0pmg.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.12.26365370",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.10.12.26365370v1.full",
  "id": "83g47pt4c0pmg",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.10.12.26365370v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "surgery"
    ],
    [
      "openalex",
      "2740|Gastric Cancer Management and Outcomes"
    ]
  ],
  "openalex": "W7221814380",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.10.12.26365370v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-12",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/83g47pt4c0pmg.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:50Z",
      "native_id": "10.64898/2026.10.12.26365370",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.10.12.26365370v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:surgery",
      "subfield": "surgery"
    }
  ],
  "title": "Stage-specific overall survival with complete five-year follow-up after D2 gastrectomy for gastric cancer at a referral hospital in Shanghai, China: a reference for comparing hospitals",
  "title_text": "Stage-specific overall survival with complete five-year follow-up after D2 gastrectomy for gastric cancer at a referral hospital in Shanghai, China: a reference for comparing hospitals",
  "type": "preprint",
  "updated_at": "2026-10-30T12:20:50Z",
  "url": "https://research.draconitic.com/paper/83g47pt4c0pmg",
  "venue": "medRxiv",
  "versions": []
}