{
  "abstract": "Background\n\nDexmedetomidine is a selective alpha-2 adrenergic agonist used primarily for intravenous sedation in intensive care units and during surgical or diagnostic procedures.\n\nMethods\n\nThis prospective randomized study was carried out on 90 adult patients aged 65 years and older who presented to the operating room for surgery under general anesthesia. Patients were divided into two equal groups. Group (A) received general anesthesia after infusion of normal saline, while group (B) received general anesthesia after a loading dose of dexmedetomidine 0.6 µg/kg.\n\nResults\n\nThere was a statistically significant decrease in hemodynamic parameters observed in the two groups after induction of anesthesia. Dexmedetomidine administration resulted in a further significant decrease in these parameters when compared to the control group. These changes were not clinically significant, as the values remained within normal ranges. This effect may be beneficial in elderly patients undergoing surgery under general anesthesia.\n\nConclusion\n\nDexmedetomidine provided superior hemodynamic stability compared with the control group.",
  "abstract_shown": true,
  "affiliations": [
    "Anesthesiology, Intensive Care and Pain managment Department, Faculty of Medicine. Minia University, Minia, Egypt",
    "Anesthesia and intensive care faculty of medicine Minia university Minia Egypt",
    "anesthesia,Medicine, Minia University",
    "Anesthesia and ICU department, Minia University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Arwa Anwar"
    },
    {
      "affs": [
        1
      ],
      "name": "Tarek Abdelzaher"
    },
    {
      "affs": [
        2
      ],
      "name": "amr nady"
    },
    {
      "affs": [
        3
      ],
      "name": "Ibrahim Talaat"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/83mp3y7vgs6wz.bib",
  "cited_by": 0,
  "doi": "10.21608/mjmr.2026.537579.2408",
  "fulltext_url": "https://mjmr.journals.ekb.eg/article_534504.html",
  "id": "83mp3y7vgs6wz",
  "issns": [
    "2682-4558"
  ],
  "landing_url": "https://doi.org/10.21608/mjmr.2026.537579.2408",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2703|Anesthesia and Sedative Agents"
    ]
  ],
  "openalex": "W7222872809",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": "Minia University, Faculty of Medicine",
  "ris": "https://research.draconitic.com/paper/83mp3y7vgs6wz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:12Z",
      "native_id": "4ec380a4fc2a43239df79dfe867671d4",
      "source": "doaj",
      "url": "https://doi.org/10.21608/mjmr.2026.537579.2408"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2703|Anesthesia and Sedative Agents",
      "subfield": "surgery"
    }
  ],
  "title": "Intraoperative hemodynamic changes in patients receiving dexmedetomidine for general anesthesia.",
  "title_text": "Intraoperative hemodynamic changes in patients receiving dexmedetomidine for general anesthesia.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:12Z",
  "url": "https://research.draconitic.com/paper/83mp3y7vgs6wz",
  "venue": "Minia Journal of Medical Research",
  "versions": []
}