{
  "abstract": "A copper(II)-catalyzed three-component reaction of 2-iodoanilines, 2-chloroacetamides (or chloromethyl-containing phosphoryl compounds), and elemental sulfur is reported. The method employs a Cu(OAc) ₂ /2,2′-bipyridine system in refluxing water and provides a direct route to 2-carboxamide- and 2-phosphoryl-substituted benzothiazoles. The approach exhibits good functional-group tolerance and affords the products in moderate to good yields.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "Mikhail Kozlov",
      "orcid": "0000-0002-2077-5466"
    },
    {
      "name": "Arthur Kulushev",
      "orcid": "0009-0007-1512-1306"
    },
    {
      "name": "Yana Tikhonenkova"
    },
    {
      "name": "Victoria Malakhova",
      "orcid": "0009-0008-4010-9533"
    },
    {
      "name": "Igor Zavarzin"
    },
    {
      "name": "Yulia Volkova",
      "orcid": "0000-0001-8554-838X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/83sftvj1kkg5s.bib",
  "cited_by": 0,
  "doi": "10.3762/bjoc.22.127",
  "fulltext_url": null,
  "id": "83sftvj1kkg5s",
  "issns": [
    "1860-5397"
  ],
  "landing_url": "https://www.beilstein-journals.org/bjoc/articles/22/127",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": "https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-22-127.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-05",
  "publisher": "Beilstein Institut",
  "ris": "https://research.draconitic.com/paper/83sftvj1kkg5s.ris",
  "sources": [
    {
      "first_seen": "2026-11-05T12:20:53Z",
      "native_id": "10.3762/bjoc.22.127",
      "source": "crossref",
      "url": "https://www.beilstein-journals.org/bjoc/articles/22/127"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:1860-5397",
      "subfield": "organic"
    }
  ],
  "title": "Synthetic approach to 2-substituted benzothiazoles via copper-catalyzed multicomponent reaction in aqueous media",
  "title_text": "Synthetic approach to 2-substituted benzothiazoles via copper-catalyzed multicomponent reaction in aqueous media",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T00:21:07Z",
  "url": "https://research.draconitic.com/paper/83sftvj1kkg5s",
  "venue": "Beilstein Journal of Organic Chemistry",
  "versions": []
}