{
  "abstract": "Background: Coronavirus disease 2019 (COVID-19) has become an important issue in immunocompromised patients owing to the high transmissibility of severe acute respiratory syndrome coronavirus 2. Sarcopenia in lung transplant patients is associated with a poor prognosis, and patients who have undergone lung transplant are more vulnerable to COVID-19. This study aimed to investigate the association of sarcopenia with clinical outcomes in lung transplant patients with COVID-19 and the risk factors for sarcopenia following COVID-19 in lung transplant patients.\n\nMethods: We performed a retrospective cohort study of lung transplant patients with COVID-19. Sarcopenia was defined as being within the lower 25% of the thoracic muscle index based on cross-sectional area measurements at the fourth vertebra using computed tomography (CT). Multivariable logistic analysis was conducted to identify factors associated with sarcopenia in lung transplant patients with COVID-19.\n\nResults: Of the 445 patients who received follow-up care after lung transplantation, 81 were diagnosed with COVID-19. Among patients within three years of lung transplantation, the sarcopenia group had a significantly higher rate of hospitalisation (100.0% vs. 46.9%, P = 0.006) and oxygen demand (63.6% vs. 18.8%, P = 0.016) than the non-sarcopenia group. Body mass index before COVID-19 (odds ratio [OR], 0.77; confidence interval [CI], 0.58–0.96; P = 0.040) and serum albumin (OR, 0.12; CI, 0.01–0.79; P = 0.047) were significantly associated with sarcopenia after COVID-19.\n\nConclusions: Sarcopenia is associated with poor COVID-19 outcomes in patients within three years after lung transplantation. Assessment and intervention for sarcopenia are required to improve the prognosis of patients undergoing lung transplantation for COVID-19.\n\nSupplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12890-026-04563-x.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 03722 Republic of Korea",
    "Division of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Republic of Korea",
    "Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 03722 Republic of Korea",
    "Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, 03722 Republic of Korea"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Se Ju Lee"
    },
    {
      "affs": [
        2
      ],
      "name": "Ala Woo"
    },
    {
      "affs": [
        0
      ],
      "name": "Jung Ah Lee"
    },
    {
      "affs": [
        0
      ],
      "name": "Chang Hyup Kim"
    },
    {
      "affs": [
        0
      ],
      "name": "Jinnam Kim"
    },
    {
      "affs": [
        0
      ],
      "name": "Ki Hyun Lee"
    },
    {
      "affs": [
        3
      ],
      "name": "Ha Eun Kim"
    },
    {
      "affs": [
        3
      ],
      "name": "Jin Gu Lee"
    },
    {
      "affs": [
        2
      ],
      "name": "Song Yee Kim"
    },
    {
      "affs": [
        2
      ],
      "name": "Moo Suk Park"
    },
    {
      "affs": [
        0
      ],
      "name": "Su Jin Jeong",
      "orcid": "0000-0003-4025-4542"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/84qewr02y5pec.bib",
  "cited_by": 0,
  "doi": "10.1186/s12890-026-04563-x",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13733035/",
  "id": "84qewr02y5pec",
  "issns": [
    "1471-2466"
  ],
  "landing_url": "https://doi.org/10.1186/s12890-026-04563-x",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
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      "lcc",
      "RC705-779"
    ],
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      "openalex",
      "2737|Nutrition and Health in Aging"
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  "openalex": "W7201995803",
  "pdf_url": null,
  "pmcid": "PMC13733035",
  "pmid": "42983689",
  "published": "2026-08-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/84qewr02y5pec.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:22:54Z",
      "native_id": "PMC13733035",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s12890-026-04563-x"
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    {
      "first_seen": "2026-11-08T14:20:53Z",
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  "subjects": [
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      "field": "medicine",
      "origin": "openalex:2737|Nutrition and Health in Aging",
      "subfield": "physiology"
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  "title": "The association of decreased thoracic muscle mass with unfavourable outcomes in lung transplant patients with COVID-19: a retrospective cohort study",
  "title_text": "The association of decreased thoracic muscle mass with unfavourable outcomes in lung transplant patients with COVID-19: a retrospective cohort study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-10T14:20:58Z",
  "url": "https://research.draconitic.com/paper/84qewr02y5pec",
  "venue": "BMC Pulmonary Medicine",
  "versions": []
}