{
  "abstract": "Background\n\nPsoriasis is a chronic inflammatory skin disease mediated by immune dysregulation, with a prolonged course, high recurrence rate, and limited curative options. Biologics are effective but costly, carry immunosuppressive risks, and are associated with relapse after discontinuation.Objective\n\nTo review the potential mechanisms by which food-derived substances and edible Chinese medicinal materials improve psoriasis through immunomodulation, oxidative stress mitigation, and gut microbiota regulation, and to grade the clinical evidence descriptively.Methods\n\nThis is a narrative review, not a systematic review. Literature was searched in PubMed, Web of Science, Cochrane Library, CNKI, and Wanfang up to June 2026. Search terms included psoriasis, diet, nutrition, microbiota, metabolism, and Traditional Chinese Medicine. Evidence grading was informed by the GRADE framework, but no formal GRADE assessment was performed.Main findings\n\nThe Mediterranean diet and weight-loss interventions have relatively higher levels of evidence. Omega-3 polyunsaturated fatty acids, bioavailable curcumin, specific probiotic strains, and some medicine-food homologous Chinese herbs show potential adjunctive benefits, but most studies are small, single-center, and lack blinding. Traditional applications of honeysuckle, wolfberry, and Coix seed are gradually being explained by modern pharmacology.Conclusion\n\nDietary and medicine-food homologous interventions may serve as adjuncts in psoriasis management but cannot replace conventional treatment. High-quality multicenter RCTs are needed to confirm efficacy and safety.",
  "abstract_shown": true,
  "affiliations": [
    "The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, People's Republic of China.",
    "Department of Dermatology, Gansu Provincial People's Hospital, Lanzhou, Gansu, People's Republic of China."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Xiaoqin Ma"
    },
    {
      "affs": [
        0
      ],
      "name": "Shuniu Zheng",
      "orcid": "0009-0002-1278-276X"
    },
    {
      "affs": [
        0
      ],
      "name": "Jinjin Kai"
    },
    {
      "affs": [
        1
      ],
      "name": "Xianwei Wu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/85f35dxxfsneg.bib",
  "cited_by": 0,
  "doi": "10.2147/ccid.s643906",
  "fulltext_url": "https://europepmc.org/articles/PMC13695944",
  "id": "85f35dxxfsneg",
  "issns": [
    "1178-7015"
  ],
  "landing_url": "https://europepmc.org/article/MED/42928794",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2403|Psoriasis: Treatment and Pathogenesis"
    ]
  ],
  "openalex": "W7223121360",
  "pdf_url": "https://europepmc.org/articles/PMC13695944?pdf=render",
  "pmcid": "PMC13695944",
  "pmid": "42928794",
  "published": "2026-10-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/85f35dxxfsneg.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42928794",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42928794"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2403|Psoriasis: Treatment and Pathogenesis",
      "subfield": "immunology"
    }
  ],
  "title": "Food-Derived Substances and Edible Chinese Medicinal Materials in Psoriasis Management: Potential, Evidence, and Perspectives-A Narrative Review.",
  "title_text": "Food-Derived Substances and Edible Chinese Medicinal Materials in Psoriasis Management: Potential, Evidence, and Perspectives-A Narrative Review.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/85f35dxxfsneg",
  "venue": "Clinical, cosmetic and investigational dermatology",
  "versions": []
}