{
  "abstract": "A stereospecific, Lewis acid-catalyzed intramolecular nucleophilic substitution at fully substituted carbon stereocenters is described, proceeding through nonclassical cyclopropyl carbinyl (CPC) carbocation intermediates and complete skeletal rearrangement. The method displays excellent regio- and diastereoselectivity, offering a general strategy for exploiting nonclassical carbocations in stereoselective synthesis.",
  "abstract_shown": true,
  "affiliations": [
    "Technion−Israel Institute of Technology , , ,"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Kaushalendra Patel"
    },
    {
      "affs": [
        0
      ],
      "name": "Belal Awwad"
    },
    {
      "affs": [
        0
      ],
      "name": "Ilan Marek",
      "orcid": "0000-0001-9154-2320"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/85vpq23dj2v6n.bib",
  "cited_by": 0,
  "doi": "10.1021/jacsau.6c00439",
  "fulltext_url": "https://europepmc.org/articles/PMC13714854",
  "id": "85vpq23dj2v6n",
  "issns": [
    "2691-3704"
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  "landing_url": "https://pubs.acs.org/jaaucr/article/6/10/5571/5448615/Intramolecular-Stereospecific-Skeletal",
  "language": "eng",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Letter"
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    [
      "openalex",
      "1605|Cyclopropane Reaction Mechanisms"
    ]
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  "openalex": "W7221438797",
  "pdf_url": "https://pubs.acs.org/doi/pdf/10.1021/jacsau.6c00439",
  "pmcid": "PMC13714854",
  "pmid": "42953149",
  "published": "2026-10-11",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/85vpq23dj2v6n.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:36Z",
      "native_id": "10.1021/jacsau.6c00439",
      "source": "crossref",
      "url": "https://pubs.acs.org/jaaucr/article/6/10/5571/5448615/Intramolecular-Stereospecific-Skeletal"
    },
    {
      "first_seen": "2026-10-31T00:20:41Z",
      "native_id": "MED:42953149",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42953149"
    },
    {
      "first_seen": "2026-11-01T12:22:16Z",
      "native_id": "PMC13714854",
      "source": "pmc",
      "url": "https://doi.org/10.1021/jacsau.6c00439"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Cyclopropane Reaction Mechanisms",
      "subfield": "organic"
    }
  ],
  "title": "Intramolecular Stereospecific Skeletal Rearrangement via Nonclassical Carbocations",
  "title_text": "Intramolecular Stereospecific Skeletal Rearrangement via Nonclassical Carbocations",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:22:16Z",
  "url": "https://research.draconitic.com/paper/85vpq23dj2v6n",
  "venue": "JACS Au",
  "versions": []
}