{
  "abstract": "BACKGROUNDIndigenous tribes face a disproportionately high tuberculosis (TB) burden due to deep-rooted socioeconomic disadvantage, highlighting the need for strengthened surveillance and control strategies.\n\nMETHODSWe conducted a 21-year retrospective study (2005-2025) among tribal and neighboring non-tribal populations attending a tribal-serving hospital in Karnataka. Pre-Nikshay data were transcribed from paper registers, and post-Nikshay data were obtained from the digital system. We assessed negative binomial interrupted time-series regression model, data completeness, TB risk factors, and used multivariable logistic regression to identify determinants of poor treatment outcomes and household contact screening yield.\n\nRESULTSWe analyzed 1,512 TB cases (tribal = 1,021; non-tribal = 491). TB detection increased significantly over time, with a steeper rise among tribal populations (p<0.001). Nikshay implementation significantly improved data completeness (Wilcoxon W = 9900, p<0.001). Among tribal patients, males had higher odds of poor treatment outcome (aOR 2.81, 95% CI 1.70-4.85; p<0.001). Diabetes (aOR 2.10, 95% CI 1.05-4.03; p=0.029) was independently associated with poor treatment outcome. Among 503 index cases, 1,535 household contacts were identified and 1,161 (75.6%) screened; coverage was lower among tribal contacts (69.8% vs 87.2%; p<0.001).\n\nCONCLUSIONSNikshay strengthened TB surveillance and improved assessment of TB burden and risk factors in tribal communities.",
  "abstract_shown": true,
  "affiliations": [
    "1. Manipal Academy of Higher Education, Manipal, Karnataka, India 2. Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "name": "M. Rastogi"
    },
    {
      "name": "A. S. Babu"
    },
    {
      "name": "A. R"
    },
    {
      "name": "S. Vasanthaiah"
    },
    {
      "name": "P. Ponnusamy"
    },
    {
      "name": "N. N"
    },
    {
      "name": "R. M"
    },
    {
      "name": "D. Murthy"
    },
    {
      "name": "A. Pandey"
    },
    {
      "name": "K. G. Suryanarayana"
    },
    {
      "affs": [
        0
      ],
      "name": "R. Verma"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8600ny99hkzfw.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.13.26365279",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365279v1.full",
  "id": "8600ny99hkzfw",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365279v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "infectious diseases"
    ],
    [
      "openalex",
      "2725|Tuberculosis Research and Epidemiology"
    ]
  ],
  "openalex": "W7221881081",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365279v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-13",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/8600ny99hkzfw.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:57Z",
      "native_id": "10.64898/2026.10.13.26365279",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365279v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:infectious diseases",
      "subfield": "infectious-disease"
    }
  ],
  "title": "IMPACT OF CENTRALIZED NIKSHAY ON TB NOTIFICATION AND DATA COMPLETENESS IN INDIGENOUS TRIBES: A 21-YEAR STUDY",
  "title_text": "IMPACT OF CENTRALIZED NIKSHAY ON TB NOTIFICATION AND DATA COMPLETENESS IN INDIGENOUS TRIBES: A 21-YEAR STUDY",
  "type": "preprint",
  "updated_at": "2026-10-30T12:20:57Z",
  "url": "https://research.draconitic.com/paper/8600ny99hkzfw",
  "venue": "medRxiv",
  "versions": []
}