{
  "abstract": "Background: Coronary computed tomography angiography (CCTA) is increasingly used for the evaluation of coronary artery disease; however, radiation exposure remains a patient safety concern. Data on radiation dose optimization from low- and middle-income countries are limited.\n\nProject Rationale: Tabba Heart Institute Karachi identified opportunities to reduce CCTA radiation exposure through implementation of heart rate and body mass index–guided acquisition protocols while maintaining image quality.\n\nProject Summary: A quality improvement initiative was implemented using patient-specific scanning protocols. A total of 422 CCTA examinations were evaluated, including 117 preintervention and 305 postintervention studies. Median effective radiation dose decreased by 45.5%, from 8.8 mSv to 4.8 mSv (P < 0.001). CCTA dose-length product decreased by 46.5% and total dose-length product by 39.8% (both P < 0.001). No significant differences were observed in image quality metrics or repeat scan rates.\n\nTake-Home Message: Technologist-driven protocol optimization can substantially reduce CCTA radiation exposure without compromising image quality and may serve as a scalable model for cardiovascular imaging programs in resource-constrained settings.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan",
    "Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan",
    "Consultant Cardiologist and Director Radiology Tabba Heart Institute, Karachi, Pakistan"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Muhammad Kashif"
    },
    {
      "affs": [
        1
      ],
      "name": "Danish Waris Ali"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Adeel Ur Rahman Siddiqui"
    },
    {
      "affs": [
        1
      ],
      "name": "Muhammad Ali"
    },
    {
      "affs": [
        1
      ],
      "name": "Sumair Ahmed"
    },
    {
      "affs": [
        0
      ],
      "name": "Muhammad Arshad"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Bashir Hanif"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/862aqcb2ae1gj.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jaccas.2026.109329",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13728305/",
  "id": "862aqcb2ae1gj",
  "issns": [
    "2666-0849"
  ],
  "landing_url": "https://doi.org/10.1016/j.jaccas.2026.109329",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Imaging"
    ],
    [
      "heading",
      "Quality Improvement Projects"
    ],
    [
      "openalex",
      "2741|Radiation Dose and Imaging"
    ]
  ],
  "openalex": "W7213435938",
  "pdf_url": null,
  "pmcid": "PMC13728305",
  "pmid": "42752009",
  "published": "2026-09-16",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/862aqcb2ae1gj.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T12:24:01Z",
      "native_id": "PMC13728305",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.jaccas.2026.109329"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2741|Radiation Dose and Imaging",
      "subfield": "imaging"
    }
  ],
  "title": "Radiation Dose Optimization in Coronary CT Angiography",
  "title_text": "Radiation Dose Optimization in Coronary CT Angiography",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:19Z",
  "url": "https://research.draconitic.com/paper/862aqcb2ae1gj",
  "venue": "JACC Case Reports",
  "versions": []
}