{
  "abstract": "The vinegar fly, Drosophila melanogaster, has contributed tremendously to advancing our understanding of the fundamentals of biology, from the chromosomal theory of inheritance to the survival of multi-cellular organisms in spaceflight. The use of this insect as a model organism has provided insights into all branches of life sciences, including agricultural and environmental sciences. In the context of integrated pest management (IPM), which often relies on species-specific natural history and phenology of pest insects and biological control, D. melanogaster flies have continued to be a powerhouse. In this review, we seek to summarize the use of the D. melanogaster model in studying insect biology relevant to IPM, with a focus on investigating the mechanisms underlying insecticide resistance. We sample case studies that adopt forward genetic approaches to reveal molecular underpinnings of IPM-relevant phenotypes and reverse genetic approaches that elucidate genotype-phenotype relationships. In particular, we highlight the contribution of D. melanogaster in understanding the biology and in developing IPM for the spotted-wing drosophila, also known as D. suzukii, a pest Drosophila species that devastates fruit production worldwide. Finally, we summarize recently developed research tools and resources in D. melanogaster that have potential utility for agricultural pest management.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Entomology and Nematology, College of Agricultural and Environmental Sciences, University of California Davis, Davis, CA, USA."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yao D Cai",
      "orcid": "0000-0002-3571-2978"
    },
    {
      "affs": [
        0
      ],
      "name": "Joanna C Chiu",
      "orcid": "0000-0001-7613-8127"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/87nagv1pbx0w6.bib",
  "cited_by": 0,
  "doi": "10.1080/19336934.2026.2749209",
  "fulltext_url": "https://europepmc.org/articles/PMC13690281",
  "id": "87nagv1pbx0w6",
  "issns": [
    "1933-6934",
    "1933-6942"
  ],
  "landing_url": "https://europepmc.org/article/MED/42902760",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1109|Insect behavior and control techniques"
    ]
  ],
  "openalex": "W7223155970",
  "pdf_url": "https://europepmc.org/articles/PMC13690281?pdf=render",
  "pmcid": "PMC13690281",
  "pmid": "42902760",
  "published": "2026-10-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/87nagv1pbx0w6.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42902760",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42902760"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1109|Insect behavior and control techniques",
      "subfield": "zoology-behaviour"
    }
  ],
  "title": "From bench to farm: leveraging Drosophila as a model insect for agricultural pest management.",
  "title_text": "From bench to farm: leveraging Drosophila as a model insect for agricultural pest management.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/87nagv1pbx0w6",
  "venue": "Fly",
  "versions": []
}