{
  "abstract": "Objective\n\nThis study aimed to evaluate the effect of LV in combination with gabapentin, a first-line medication for RLS, on the treatment of patients with the condition.Results\n\nIn total, 36 participants (18 in each group) participated in this study, with 10 (55%) being male within each group. The mean age of participants was 45 years (SD = 10.6) in the LV group and 49.1 (SD = 8.3) in the gabapentin group. In both the LV and gabapentin groups, IRLSSG scores decreased significantly after the intervention compared with baseline (p < 0.001). However, scores increased at the one-month follow-up, although they remained lower than pre-intervention values (p < 0.001). A similar pattern was observed for the PSQI scores (p < 0.001). There were no significant differences between groups at any timepoint (p > 0.05).Trial registration\n\nThe study protocol was registered at the Iranian Registry of Clinical Trials on August 30th, 2023 (code IRCT20190306042945N4).",
  "abstract_shown": true,
  "affiliations": [
    "Neuromusculoskeletal Research Center, Department of Physical Medicine and Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.",
    "Neuromusculoskeletal Research Center, Department of Physical Medicine and Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. forogh.b@iums.ac.ir.",
    "Neuromusculoskeletal Research Center, Department of Physical Medicine and Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. hamida2091@gmail.com.",
    "Clinical Biomechanics and Ergonomics Research Center, Department of Physical Medicine and Rehabilitation, AJA University of Medical Sciences, Tehran, Iran."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Gholamreza Raissi"
    },
    {
      "affs": [
        1
      ],
      "name": "Bijan Forogh"
    },
    {
      "affs": [
        2
      ],
      "name": "Hamid Ansari"
    },
    {
      "affs": [
        0
      ],
      "name": "Seyed Pezhman Madani"
    },
    {
      "affs": [
        3
      ],
      "name": "Masumeh Bagherzadeh Cham"
    },
    {
      "affs": [
        0
      ],
      "name": "Hosna Soleymanzadeh"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/886rgft7z2320.bib",
  "cited_by": 0,
  "doi": "10.1186/s13104-026-07918-z",
  "fulltext_url": "https://europepmc.org/articles/PMC13688849",
  "id": "886rgft7z2320",
  "issns": [
    "1756-0500"
  ],
  "landing_url": "https://europepmc.org/article/MED/42908006",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "Q1-390"
    ],
    [
      "lcc",
      "QH301-705.5"
    ],
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2713|Restless Legs Syndrome Research"
    ]
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  "openalex": "W7171357517",
  "pdf_url": "https://europepmc.org/articles/PMC13688849?pdf=render",
  "pmcid": "PMC13688849",
  "pmid": "42908006",
  "published": "2026-07-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/886rgft7z2320.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:57Z",
      "native_id": "MED:42908006",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42908006"
    },
    {
      "first_seen": "2026-10-30T13:45:38Z",
      "native_id": "c9512b4905d349bb87b2ae7ee7259fc6",
      "source": "doaj",
      "url": "https://doi.org/10.1186/s13104-026-07918-z"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Restless Legs Syndrome Research",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Effects of local vibration therapy and gabapentin on restless legs syndrome symptoms: a randomized controlled trial.",
  "title_text": "Effects of local vibration therapy and gabapentin on restless legs syndrome symptoms: a randomized controlled trial.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:38Z",
  "url": "https://research.draconitic.com/paper/886rgft7z2320",
  "venue": "BMC research notes",
  "versions": []
}