{
  "abstract": "Introduction\n\nThis scoping review maps evidence for microbiome-driven precision psychiatry in depression and anxiety.Methods\n\nFollowing JBI guidance and PRISMA-ScR, we searched PubMed/MEDLINE and PubMed Central from inception to July 2026, supplemented by Google Scholar and backward citation searching. Human primary studies were screened and charted; findings were synthesized narratively.Results\n\nOf 58 identified records, 49 remained after deduplication, 35 full texts were assessed, and 28 studies were included. The evidence was predominantly observational. Taxonomic findings varied across populations, while studies of microbial functions, metabolites, multi-omics signatures, and treatment response suggested potential for biological stratification. Microbiome-targeted interventions and artificial intelligence models remain exploratory.Discussion\n\nMicrobiome-derived biomarkers and predictive models require standardized methods, independent validation, and prospective evidence of clinical utility before routine psychiatric use.",
  "abstract_shown": true,
  "affiliations": [
    "General Practice Department, The Second People's Hospital of Changde City , ,",
    "Department of General Practice, The First Affiliated Hospital of Changde Vocational and Technical College , ,",
    "Medical Affairs Department, The Second People's Hospital of Changde City , ,",
    "Department of General Medicine, Xiangya Hospital, Central South University , ,"
  ],
  "article_type": "systematic review",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yi Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Changyong Pei"
    },
    {
      "affs": [
        2
      ],
      "name": "Daohua Zhang"
    },
    {
      "affs": [
        3
      ],
      "name": "Jun Liu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/88he38kbzk19x.bib",
  "cited_by": 0,
  "doi": "10.3389/fmed.2026.1957715",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13716581/?tool=EBI",
  "id": "88he38kbzk19x",
  "issns": [
    "2296-858X"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13716581",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Systematic Review"
    ],
    [
      "openalex",
      "1312|Gut microbiota and health"
    ]
  ],
  "openalex": "W7222269740",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13716581/pdf/?tool=EBI",
  "pmcid": "PMC13716581",
  "pmid": "42959082",
  "published": "2026-10-15",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/88he38kbzk19x.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:37Z",
      "native_id": "PMC:PMC13716581",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13716581"
    },
    {
      "first_seen": "2026-11-01T00:20:52Z",
      "native_id": "MED:42959082",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42959082"
    },
    {
      "first_seen": "2026-11-01T12:23:50Z",
      "native_id": "PMC13716581",
      "source": "pmc",
      "url": "https://doi.org/10.3389/fmed.2026.1957715"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Gut microbiota and health",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis",
  "title_text": "Microbiome-driven precision psychiatry: integrating multi-omics, artificial intelligence, and personalized interventions along the gut-brain axis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:21:04Z",
  "url": "https://research.draconitic.com/paper/88he38kbzk19x",
  "venue": "Frontiers in medicine",
  "versions": []
}