{
  "abstract": "Primary hepatic perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm that can mimic common hepatic malignancies. A 28-year-old African woman with colorectal cancer in remission presented with 3 months of epigastric pain and tender hepatomegaly. Tumor markers were normal. Ultrasound and triphasic CT showed 2 large heterogeneous hypervascular hepatic masses with progressive enhancement and early venous drainage; hepatobiliary iminodiacetic acid scan (HIDA) SPECT-CT demonstrated photopenic lesions. Biopsy revealed epithelioid cells with focal HMB45, diffuse smooth muscle actin, and Ki-67 20%–30%, confirming hepatic PEComa. Resection was feasible but deferred; everolimus was started before loss to follow-up.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, The Aga Khan University Hospital Nairobi, Nairobi, Kenya",
    "Department of Medicine, The Aga Khan University Hospital Nairobi, Nairobi, Kenya",
    "Department of Pathology, The Aga Khan University Hospital Nairobi, Nairobi, Kenya",
    "Department of Haemato-Oncology, The Aga Khan University Hospital Nairobi, Nairobi, Kenya"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Gerald Odong",
      "orcid": "0009-0004-1690-0684"
    },
    {
      "affs": [
        1
      ],
      "name": "Priyanka Panwar",
      "orcid": "0009-0000-8493-0683"
    },
    {
      "affs": [
        1
      ],
      "name": "Lavender Otom",
      "orcid": "0009-0003-4105-9068"
    },
    {
      "affs": [
        0
      ],
      "name": "Ivy Wakahora",
      "orcid": "0009-0006-4237-2680"
    },
    {
      "affs": [
        0
      ],
      "name": "Steven Idet",
      "orcid": "0009-0004-4224-3470"
    },
    {
      "affs": [
        0
      ],
      "name": "Sarah Kibe"
    },
    {
      "affs": [
        2
      ],
      "name": "Patricia Okiro",
      "orcid": "0000-0001-6060-3979"
    },
    {
      "affs": [
        1
      ],
      "name": "Saleem Abdulkarim",
      "orcid": "0000-0001-7427-1098"
    },
    {
      "affs": [
        1
      ],
      "name": "Ajua Alemanji",
      "orcid": "0009-0007-4546-9899"
    },
    {
      "affs": [
        3
      ],
      "name": "Amina Kidee",
      "orcid": "0009-0008-4759-8528"
    },
    {
      "affs": [
        0
      ],
      "name": "Samuel Gitau",
      "orcid": "0000-0002-8908-4735"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8bvrca8wwcts5.bib",
  "cited_by": 0,
  "doi": "10.14309/crj.0000000000002377",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13734556/",
  "id": "8bvrca8wwcts5",
  "issns": [
    "2326-3253"
  ],
  "landing_url": "https://doi.org/10.14309/crj.0000000000002377",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "heading",
      "Liver"
    ],
    [
      "openalex",
      "2716|Tuberous Sclerosis Complex Research"
    ]
  ],
  "openalex": "W7225226120",
  "pdf_url": null,
  "pmcid": "PMC13734556",
  "pmid": "42985675",
  "published": "2026-11-04",
  "publisher": "American College of Gastroenterology",
  "ris": "https://research.draconitic.com/paper/8bvrca8wwcts5.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:24:00Z",
      "native_id": "PMC13734556",
      "source": "pmc",
      "url": "https://doi.org/10.14309/crj.0000000000002377"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2716|Tuberous Sclerosis Complex Research",
      "subfield": "human-genetics"
    }
  ],
  "title": "Diagnostic Challenge of Primary Hepatic PEComa in a Young Woman with Prior Colorectal Cancer",
  "title_text": "Diagnostic Challenge of Primary Hepatic PEComa in a Young Woman with Prior Colorectal Cancer",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:24:00Z",
  "url": "https://research.draconitic.com/paper/8bvrca8wwcts5",
  "venue": "ACG Case Reports Journal",
  "versions": []
}