{
  "abstract": "Purpose: The International Myopia Institute definition for premyopia includes a spherical equivalent refraction (SER) range of greater than −0.50 to +0.75 diopters (D), based largely on data from North American children. Whether this range is appropriate for children in other regions is uncertain.\n\nMethods: We pooled individual-level longitudinal data from three prospective studies of children in southern China: the Guangzhou Twin Eye Study, the Guangzhou Longitudinal Outdoor Activity Study, and the Zengcheng School Myopia Study. Children aged 6 to 12 years who were nonmyopic at baseline and had at least two follow-up visits were included.\n\nResults: Of the 6550 children included (45.5% girls), mean (SD) baseline age was 7.98 (2.03) years, and median follow-up was 3.0 (interquartile range, 2.0–5.0) years. During follow-up, 2587 children (39.5%) developed myopia. The optimal baseline SER for predicting future myopia varied systematically by baseline age and follow-up duration: thresholds became more hyperopic with longer follow-up and less hyperopic with older baseline age. For predicting myopia over approximately 3 to 5 years, the optimal SER cutoff was around +1.00 D for children aged 6 to 7 years, +0.75 D for those aged 8 to 9 years, and from +0.37 D to +0.75 D for those aged 10 to 12 years. The model area under the curve ranged from 0.791 to 0.958.\n\nConclusions: The optimal SER cutoff for predicting future myopia onset depends on age and population. In Chinese children, +1.00 D is a more appropriate cutoff value for defining premyopia among children in the early years of primary school.",
  "abstract_shown": true,
  "affiliations": [
    "Research School of Biology, Australian National University, Canberra, Australia",
    "School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China",
    "Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China",
    "Centre for Eye and Vision Research, Hong Kong, China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Xiaotong Han"
    },
    {
      "name": "Jiaqing Zhang"
    },
    {
      "name": "Ling Jin"
    },
    {
      "affs": [
        0
      ],
      "name": "Ian G. Morgan"
    },
    {
      "name": "Shiran Zhang"
    },
    {
      "name": "Yin Hu"
    },
    {
      "name": "Decai Wang"
    },
    {
      "name": "Yangfa Zeng"
    },
    {
      "affs": [
        1,
        2,
        3
      ],
      "name": "Mingguang He"
    },
    {
      "name": "Xiaohu Ding"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8cre9jvqr2r1z.bib",
  "cited_by": 0,
  "doi": "10.1167/iovs.67.12.55",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13715932/",
  "id": "8cre9jvqr2r1z",
  "issns": [
    "0146-0404",
    "1552-5783"
  ],
  "landing_url": "https://doi.org/10.1167/iovs.67.12.55",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Clinical, Data Science and Population Health Research"
    ],
    [
      "openalex",
      "2713|Ophthalmology and Visual Impairment Studies"
    ]
  ],
  "openalex": "W7223327836",
  "pdf_url": null,
  "pmcid": "PMC13715932",
  "pmid": "42924994",
  "published": "2026-10-23",
  "publisher": "Association for Research in Vision and Ophthalmology",
  "ris": "https://research.draconitic.com/paper/8cre9jvqr2r1z.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:23:06Z",
      "native_id": "PMC13715932",
      "source": "pmc",
      "url": "https://doi.org/10.1167/iovs.67.12.55"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Ophthalmology and Visual Impairment Studies",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Longitudinal Data on Chinese Children Suggest That Cutoff Values for Defining Premyopia Should Be Age- and Location-Specific",
  "title_text": "Longitudinal Data on Chinese Children Suggest That Cutoff Values for Defining Premyopia Should Be Age- and Location-Specific",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:23:06Z",
  "url": "https://research.draconitic.com/paper/8cre9jvqr2r1z",
  "venue": "Investigative Ophthalmology & Visual Science",
  "versions": []
}