{
  "abstract": "Objective: To prospectively explore efficacy and safety of radiotherapy combined with albumin-bound paclitaxel and platinum-based chemotherapy for locoregional recurrent cervical cancer (CC).\n\nMethods: Patients with locoregional recurrent CC were enrolled in the analysis. The enrolled patients received radiotherapy and albumin-bound paclitaxel and platinum-based chemotherapy. The primary endpoint was overall survival (OS). Secondary endpoints were progression-free survival (PFS), objective response rate (ORR), and safety.\n\nResults: 99 patients were enrolled. For all patients, the 3-year PFS and 3-year OS were 48.5% and 58.6%. 17.2% of patients achieved CR and 67.7% of patients achieved PR. The ORR was 84.8%. Moreover, 10.1% of patients were confirmed SD. The DCR was 94.9%.\n\nConclusion: Locoregional recurrent CC could benefit from radiotherapy combined with albumin-bound paclitaxel and platinum-based chemotherapy.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai, 200032 China",
    "Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China",
    "Department of Digestive Endoscopic Center, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Chi Fang"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Suping Liu"
    },
    {
      "affs": [
        2
      ],
      "name": "Jie Xia"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Xiaohua Wu"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Guihao Ke"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jun Zhu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8ed25f0b2s3kv.bib",
  "cited_by": 0,
  "doi": "10.1007/s00432-026-06555-0",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13710511/",
  "id": "8ed25f0b2s3kv",
  "issns": [
    "0171-5216",
    "1432-1335"
  ],
  "landing_url": "https://doi.org/10.1007/s00432-026-06555-0",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2729|Endometrial and Cervical Cancer Treatments"
    ]
  ],
  "openalex": "W7171525825",
  "pdf_url": null,
  "pmcid": "PMC13710511",
  "pmid": "42931961",
  "published": "2026-07-28",
  "publisher": "Springer",
  "ris": "https://research.draconitic.com/paper/8ed25f0b2s3kv.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:28Z",
      "native_id": "PMC13710511",
      "source": "pmc",
      "url": "https://doi.org/10.1007/s00432-026-06555-0"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2729|Endometrial and Cervical Cancer Treatments",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Intensity-modulated radiotherapy combined with albumin-bound paclitaxel and platinum-based chemotherapy for locoregional recurrent cervical cancer: a single-institutional phase II investigator-initiated nonrandomized clinical trial",
  "title_text": "Intensity-modulated radiotherapy combined with albumin-bound paclitaxel and platinum-based chemotherapy for locoregional recurrent cervical cancer: a single-institutional phase II investigator-initiated nonrandomized clinical trial",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:28Z",
  "url": "https://research.draconitic.com/paper/8ed25f0b2s3kv",
  "venue": "Journal of Cancer Research and Clinical Oncology",
  "versions": []
}