{
  "abstract": "Background: Pyogenic arthritis of the hip joint is a rare but serious complication of invasive Streptococcus pyogenes (group A Streptococcus [GAS]) infection that may rapidly lead to joint destruction and is often difficult to diagnose early. This report describes the case of a previously healthy adult who developed GAS bloodstream infection complicated by unilateral pyogenic arthritis of the hip, temporally following an episode of sore throat.\n\nCase presentation: A 37-year-old man presented with right hip swelling, pain, and restricted mobility after a sore throat and high fever. The patient met the Sepsis-3 criteria at presentation. Magnetic resonance imaging, blood culture, and joint fluid culture results confirmed GAS bloodstream infection complicated by unilateral pyogenic arthritis of the hip. Owing to a history of skin allergic reactions to intravenous penicillin and cephalosporins, the patient was treated with intravenous meropenem, combined with ultrasound-guided joint aspiration–lavage. The patient's clinical condition improved progressively, and no recurrence was reported during 10 months of follow-up.\n\nConclusions: GAS bloodstream infection should be considered in the differential diagnosis of previously healthy adults presenting with recurrent fever and new-onset hip pain following pharyngitis. Recurrence of fever after initial defervescence may warrant evaluation for invasive bacterial infection. In patients with β-lactam allergy and documented susceptibility, meropenem may represent an option after individualized assessment. Early image-guided joint drainage, combined with appropriate systemic antimicrobial therapy such as intra-articular infusion, may contribute to infection control and preservation of joint function.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Laboratory Medicine, Guang’anmen Hospital (Baoding), No. 2699 Yuhua East Road, Lianchi, Baoding, Hebei 071000 China",
    "Department of General Practice, Guang’anmen Hospital (Baoding), Baoding, Hebei 071000 China",
    "Department of Orthopedics I, Guang’anmen Hospital (Baoding), Baoding, Hebei 071000 China"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Juan Min"
    },
    {
      "affs": [
        1
      ],
      "name": "Ying Zhao"
    },
    {
      "affs": [
        2
      ],
      "name": "Shuxing Guo"
    },
    {
      "affs": [
        0
      ],
      "name": "Chongbo Zhu"
    },
    {
      "affs": [
        0
      ],
      "name": "Zhiling Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8g7697tthydgs.bib",
  "cited_by": 0,
  "doi": "10.1186/s12891-026-10323-z",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13732875/",
  "id": "8g7697tthydgs",
  "issns": [
    "1471-2474"
  ],
  "landing_url": "https://doi.org/10.1186/s12891-026-10323-z",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2746|Orthopedic Infections and Treatments"
    ]
  ],
  "openalex": "W7196962173",
  "pdf_url": null,
  "pmcid": "PMC13732875",
  "pmid": "42983368",
  "published": "2026-08-07",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/8g7697tthydgs.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:22:46Z",
      "native_id": "PMC13732875",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s12891-026-10323-z"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Orthopedic Infections and Treatments",
      "subfield": "surgery"
    }
  ],
  "title": "Septic arthritis of the hip caused by Streptococcus pyogenes bloodstream infection in a previously healthy adult: a case report",
  "title_text": "Septic arthritis of the hip caused by Streptococcus pyogenes bloodstream infection in a previously healthy adult: a case report",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:22:46Z",
  "url": "https://research.draconitic.com/paper/8g7697tthydgs",
  "venue": "BMC Musculoskeletal Disorders",
  "versions": []
}