{
  "abstract": "Background\n\nTopical corticosteroids are acknowledged as the first-line treatment for pediatric alopecia areata. There are cases that are recalcitrant to topical corticosteroid application.Objective\n\nThe objective was to evaluate the efficacy of calcipotriol/betamethasone ointment in pediatric alopecia areata.Methods\n\nIn a 12-week retrospective study, 40 patients under 10 years old with alopecia areata were included. The patients were treated with a topical ointment combining 0.005% calcipotriol and betamethasone dipropionate once daily. The efficacy was monitored through changes in Severity of Alopecia Tool (SALT) scores.Results\n\nThe 40 patients, with a mean age of 4.1±2.1 years, were categorized by their SALT scores into two groups: those above and below 50. Patients with SALT scores over 50 showed hair regrowth in 7.44±4.44 weeks, while those with SALT scores under 50 showed regrowth in 5.71±2.58 weeks. After 12 weeks, 80.0% of the patients showed hair regrowth and 20.0% of patients showed no response or worsening. Only minor adverse events were documented during follow-up.Conclusion\n\nCalcipotriol/betamethasone ointment may represent a useful topical option for pediatric alopecia areata.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.",
    "Department of Dermatology, Pusan National University Hospital, Busan, Korea.",
    "Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.",
    "Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.",
    "Biomedical Research Institute, Pusan National University Hospital, Busan, Korea. drkmp@hanmail.net."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Yumi Won",
      "orcid": "0000-0003-3172-9913"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Jungsoo Lee",
      "orcid": "0000-0002-7519-8192"
    },
    {
      "affs": [
        0,
        1,
        3
      ],
      "name": "Hoonsoo Kim",
      "orcid": "0000-0002-7649-1446"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Hyunchang Ko",
      "orcid": "0000-0002-3459-5474"
    },
    {
      "affs": [
        0,
        1,
        3
      ],
      "name": "Byungsoo Kim",
      "orcid": "0000-0003-0054-8570"
    },
    {
      "affs": [
        0,
        1,
        4
      ],
      "name": "Moon-Bum Kim",
      "orcid": "0000-0003-4837-0214"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8jc9grk2qhs8c.bib",
  "cited_by": 0,
  "doi": "10.5021/ad.26.016",
  "fulltext_url": "https://europepmc.org/articles/PMC13655622",
  "id": "8jc9grk2qhs8c",
  "issns": [
    "1013-9087",
    "2005-3894"
  ],
  "landing_url": "https://europepmc.org/article/MED/42845204",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2748|Hair Growth and Disorders"
    ]
  ],
  "openalex": "W7203702085",
  "pdf_url": "https://europepmc.org/articles/PMC13655622?pdf=render",
  "pmcid": "PMC13655622",
  "pmid": "42845204",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/8jc9grk2qhs8c.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:10Z",
      "native_id": "MED:42845204",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42845204"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2748|Hair Growth and Disorders",
      "subfield": "general"
    }
  ],
  "title": "Efficacy of Calcipotriol/Betamethasone Ointment in the Management of Pediatric Alopecia Areata.",
  "title_text": "Efficacy of Calcipotriol/Betamethasone Ointment in the Management of Pediatric Alopecia Areata.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:10Z",
  "url": "https://research.draconitic.com/paper/8jc9grk2qhs8c",
  "venue": "Annals of dermatology",
  "versions": []
}