{
  "abstract": "BACKGROUND: Few studies have investigated the relationship between physical activity (PA) of low intensity and duration with quality of life (QoL) among individuals at risk or with cardiovascular disease (CVD). OBJECTIVES: To investigate whether PA of different intensity and duration moderates the relationship between CVD and its risk factors (obesity, hypertension, diabetes, dyslipidaemia) and QoL in adults. METHODS: Population-based cross-sectional studies using data from the EpiFloripa Cohort Study (Southern Brazil; n = 1,220, 38.8±12.0 years, 48.2% males) and the North West Adelaide Health Study (NWAHS, South Australia; n = 1,661, 43.7±11.1 years, 49.7% males). The physical and psychological domains of QoL were assessed using the WHOQOL-Bref (EpiFloripa) or the SF-36 (NWAHS) questionnaires. The diagnosis of CVD and its risk factors were self-reported. PA was self-reported and quantified by its intensity [\"walking\" or moderate/vigorous (MVPA)] and duration (none, 1-150, ≥150 min/week). Both studies were analysed separately, and results were adjusted for sociodemographic variables. RESULTS: Participants at risk or with CVD from both studies showed a lower QoL than 'healthy' individuals with a stronger relationship for the physical domain. PA duration showed a direct-trend relationship with QoL, but the associations were stronger for MVPA in both studies. However, when stratified by health status, the magnitude of the association between \"walking\" duration and a higher physical QoL was greater among those at risk or with CVD compared to 'healthy' individuals. Conversely, among Australians with CVD, MVPA was associated with a better physical QoL only when its duration was ≥150 min/week. All associations were stronger in the NWAHS than in the Brazilian study. CONCLUSIONS: \"Walking\" was more prevalent than MVPA and was consistently associated with a better physical QoL among those at risk or with CVD. These findings should be considered in the design of public health interventions designed to increase PA and improve QoL.",
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  "affiliations": [],
  "article_type": null,
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  "author_total": 7,
  "authors": [
    {
      "name": "Viviane de Menezes Caceres"
    },
    {
      "name": "Nigel Stocks"
    },
    {
      "name": "Robert Adams"
    },
    {
      "name": "Dandara Gabriela Haag"
    },
    {
      "name": "Karen Glazer Peres"
    },
    {
      "name": "Marco Aurélio Peres"
    },
    {
      "name": "David Alejandro González-Chica"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8k8z1v5ngskqf.bib",
  "cited_by": 12,
  "doi": "10.1371/journal.pone.0198769",
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  "id": "8k8z1v5ngskqf",
  "issns": [
    "1932-6203",
    "1932-6203"
  ],
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  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
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  "pdf_url": "https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198769/1/pone.0198769.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210222%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210222T095004Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-11",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/8k8z1v5ngskqf.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:54Z",
      "native_id": "hal-05791981",
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      "url": "https://hal.science/hal-05791981v1"
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  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.spee",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Physical activity moderates the deleterious relationship between cardiovascular disease, or its risk factors, and quality of life: Findings from two population-based cohort studies in Southern Brazil and South Australia",
  "title_text": "Physical activity moderates the deleterious relationship between cardiovascular disease, or its risk factors, and quality of life: Findings from two population-based cohort studies in Southern Brazil and South Australia",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:54Z",
  "url": "https://research.draconitic.com/paper/8k8z1v5ngskqf",
  "venue": "PLoS ONE",
  "versions": []
}