{
  "abstract": "Thymoma is the most common anterior mediastinal tumor, which is linked to the loss of self-tolerance and the presence of autoimmunity. Various interactions between thymoma and autoimmune diseases have been identified, including myasthenia gravis, systemic lupus erythematosus, pure red cell aplasia, and pemphigus. In this retrospective case series, we reported rare autoimmune disorders with different organ involvement associated with thymoma. These included ocular paraneoplastic pemphigus, neuromyelitis optica spectrum disorder, diffuse panbronchiolitis and myositis. Our series broadens the spectrum of autoimmune disorders with shared T cell-mediated and B cell-dependent pathogenesis, underscoring the recurrence or relapse of thymoma-associated autoimmunity. The recognition of rare autoimmune presentations charts future treatment decisions and multidisciplinary care.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Neurology, No. 2 Affiliated Hospital, Kunming Medical University",
    "Huashan Rare Disease Center and Department of Neurology, Huashan Hospital, Shanghai Medical College, National Center for Neurological Disorders, Fudan University",
    "Department of Ophthalmology, Huashan Hospital, Fudan University",
    "Department of Rheumatology, Huashan Hospital, Fudan University",
    "Department of Neurology, Zhejiang Provincial People’s Hospital, Hangzhou Medical College",
    "Department of Cardiothoracic Surgery, Huashan Hospital, Fudan University",
    "Department of Neurology, Jing’an District Centre Hospital of Shanghai"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 16,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Wenji Jia"
    },
    {
      "affs": [
        1
      ],
      "name": "Lei Jin"
    },
    {
      "affs": [
        1
      ],
      "name": "Xicheng Li"
    },
    {
      "affs": [
        1
      ],
      "name": "Dingxian He"
    },
    {
      "affs": [
        1
      ],
      "name": "Jie Song"
    },
    {
      "affs": [
        2
      ],
      "name": "Yiqin Xiao"
    },
    {
      "affs": [
        3
      ],
      "name": "Yu Xue"
    },
    {
      "affs": [
        4
      ],
      "name": "Yiqi Wang"
    },
    {
      "affs": [
        5
      ],
      "name": "Xianglin Chu"
    },
    {
      "affs": [
        6
      ],
      "name": "Hui Wu"
    },
    {
      "affs": [
        1
      ],
      "name": "Dongyue Yue"
    },
    {
      "affs": [
        1
      ],
      "name": "Wenhua Zhu"
    },
    {
      "affs": [
        1
      ],
      "name": "Jianying Xi"
    },
    {
      "affs": [
        0
      ],
      "name": "Jing Xiong"
    },
    {
      "affs": [
        1
      ],
      "name": "Chongbo Zhao"
    },
    {
      "affs": [
        1
      ],
      "name": "Sushan Luo"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8kz7x6xe4c4rq.bib",
  "cited_by": 0,
  "doi": "10.3389/fimmu.2026.1948683",
  "fulltext_url": null,
  "id": "8kz7x6xe4c4rq",
  "issns": [
    "1664-3224"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fimmu.2026.1948683/full",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2728|Myasthenia Gravis and Thymoma"
    ]
  ],
  "openalex": "W7223673283",
  "pdf_url": "https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2026.1948683/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-26",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/8kz7x6xe4c4rq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:17Z",
      "native_id": "10.3389/fimmu.2026.1948683",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fimmu.2026.1948683/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Myasthenia Gravis and Thymoma",
      "subfield": "neurology"
    }
  ],
  "title": "Rare paraneoplastic syndromes associated with thymoma: case reports and literature review",
  "title_text": "Rare paraneoplastic syndromes associated with thymoma: case reports and literature review",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:17Z",
  "url": "https://research.draconitic.com/paper/8kz7x6xe4c4rq",
  "venue": "Frontiers in Immunology",
  "versions": []
}