{
  "abstract": "Neuropeptide activity in honey bees varies with age, behavioral role, and season. The short neuropeptide F (sNPF) modulates foraging-related behaviors in summer foragers, including food intake, sucrose sensitivity, and sensory processing, but its role in other castes remains unknown. Winter bees and nurses are two phenotypes, which are considered similar due to their substantial internal energetic reserves. Yet, their appetitive profiles have never been characterized. Here, we combined electrophysiological, behavioral and neuropeptide supplementation approaches to compare appetitive behaviors across bees of different behavioral castes and ages, with or without sNPF supplementation. sNPF treatment enhanced sucrose responsiveness in winter bees and olfactory responses in nurses. Our results reveal distinct appetitive profiles, challenge the assumption that nurses and winter bees behave similarly, and highlight that appetitive motivation is multidimensional. Specifically, they show that phenotype and season can decouple peripheral sensitivity, central responsiveness, learning performance, and food consumption.",
  "abstract_shown": true,
  "affiliations": [
    "Neuro-SU, CNRS, Inserm, Sorbonne Université, Paris, France",
    "Institut de Biologie Paris-Seine, IBPS CNRS, Inserm, Sorbonne Université, Paris, France",
    "Institut d’Écologie et des Sciences de l’Environnement de Paris (UMR7618) CNRS, INRAE, IRD, Sorbonne Université, Université Paris Cité, Université Paris Est Créteil, Paris, France",
    "Departamento de Biologia, Laboratory Comportamento e Ecologia de Insetos Sociais, FFCLRP, University of São Paulo, Ribeirão Preto, SP Brazil",
    "Latin American Society for Bee Research (SOLATINA), Cochabamba, Bolivia"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Rafael C. da Silva",
      "orcid": "0000-0003-2674-8976"
    },
    {
      "affs": [
        3
      ],
      "name": "Mariana P. Cassinelli"
    },
    {
      "affs": [
        4
      ],
      "name": "Rodrigo Velarde",
      "orcid": "0000-0002-3298-824X"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Bérénice Nahmias"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Louise Bestea"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Martin Giurfa",
      "orcid": "0000-0001-7173-769X"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Maria Gabriela de Brito Sánchez",
      "orcid": "0000-0001-6940-8088"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8n3rarpmzyxmg.bib",
  "cited_by": 0,
  "doi": "10.1038/s42003-026-10484-6",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13710948/",
  "id": "8n3rarpmzyxmg",
  "issns": [
    "2399-3642"
  ],
  "landing_url": "https://doi.org/10.1038/s42003-026-10484-6",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "2804|Neurobiology and Insect Physiology Research"
    ]
  ],
  "openalex": "W7167366575",
  "pdf_url": "https://www.nature.com/articles/s42003-026-10484-6_reference.pdf",
  "pmcid": "PMC13710948",
  "pmid": "42401665",
  "published": "2026-07-04",
  "publisher": "Nature Publishing Group",
  "ris": "https://research.draconitic.com/paper/8n3rarpmzyxmg.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:48Z",
      "native_id": "PMC13710948",
      "source": "pmc",
      "url": "https://doi.org/10.1038/s42003-026-10484-6"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2804|Neurobiology and Insect Physiology Research",
      "subfield": "neuroscience"
    }
  ],
  "title": "Phenotypic and neuropeptidergic control of appetitive behavior in honey bees (Apis mellifera)",
  "title_text": "Phenotypic and neuropeptidergic control of appetitive behavior in honey bees (Apis mellifera)",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:48Z",
  "url": "https://research.draconitic.com/paper/8n3rarpmzyxmg",
  "venue": "Communications Biology",
  "versions": []
}