{
  "abstract": "Cardiac computed tomography (CCT) has emerged as a central imaging modality in the workflow for left atrial appendage occlusion (LAAO), as accurate anatomical assessment is vital for successful intervention. CCT provides superior three-dimensional (3D) anatomical detail and isotropic spatial resolution compared to traditional trans-esophageal echocardiography, enabling precise pre-procedural planning, device sizing, and identification of optimal fluoroscopic projections. Furthermore, CCT serves as a highly accurate, non-invasive tool for detecting post-procedural complications such as peri-device leaks and device-related thrombosis. Beyond conventional imaging, CCT-derived datasets now facilitate advanced computational applications, including patient-specific 3D printing, computational fluid dynamics, and finite element modeling, to predict device-tissue interactions and post-implant hemodynamics. Additionally, artificial intelligence is increasingly integrated to automate segmentation and enhance risk stratification. This review provides a comprehensive overview of the expanding role of CCT in LAAO, highlighting its contribution to procedural optimization and the transition toward personalized, engineering-driven cardiac interventions.",
  "abstract_shown": true,
  "affiliations": [
    "Bioengineering Unit, Fondazione Monasterio, 56124 Pisa, Italy.",
    "BioCardioLab, Bioengineering Unit, Fondazione Monasterio, 54100 Massa, Italy.",
    "Department of Information Engineering, University of Pisa, 56122 Pisa, Italy.",
    "Department of Civil and Environmental Engineering, Politecnico di Milano, 20133 Milan, Italy.",
    "Laboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering \"Giulio Natta\", Politecnico di Milano, 20133 Milan, Italy.",
    "Cardiology Unit, Department of Medicine, Lavagna Hospital, 16033 Lavagna, Italy.",
    "Diagnostic and Interventional Cardiology Unit, Fondazione Monasterio, 54100 Massa, Italy."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 15,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Antonella Meloni",
      "orcid": "0000-0002-2284-8585"
    },
    {
      "affs": [
        1
      ],
      "name": "Katia Capellini"
    },
    {
      "affs": [
        1
      ],
      "name": "Benigno Marco Fanni",
      "orcid": "0000-0002-8946-1983"
    },
    {
      "affs": [
        1
      ],
      "name": "Emanuele Gasparotti",
      "orcid": "0000-0003-0122-5175"
    },
    {
      "affs": [
        1
      ],
      "name": "Rossana Buongiorno"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Ilaria Verdirame"
    },
    {
      "affs": [
        3
      ],
      "name": "Lorenza Petrini",
      "orcid": "0000-0002-6349-1586"
    },
    {
      "affs": [
        4
      ],
      "name": "Giancarlo Pennati"
    },
    {
      "affs": [
        4
      ],
      "name": "Francesca Berti",
      "orcid": "0000-0001-8621-2503"
    },
    {
      "affs": [
        0
      ],
      "name": "Vincenzo Positano",
      "orcid": "0000-0001-6955-9572"
    },
    {
      "affs": [
        5
      ],
      "name": "Guido Parodi"
    },
    {
      "affs": [
        6
      ],
      "name": "Giovanni Benedetti"
    },
    {
      "affs": [
        6
      ],
      "name": "Luigi Emilio Pastormerlo"
    },
    {
      "affs": [
        6
      ],
      "name": "Sergio Berti",
      "orcid": "0000-0002-5244-0556"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Simona Celi",
      "orcid": "0000-0002-7832-0122"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8pd8a158cwekz.bib",
  "cited_by": 0,
  "doi": "10.3390/jcm15197361",
  "fulltext_url": "https://europepmc.org/articles/PMC13665372",
  "id": "8pd8a158cwekz",
  "issns": [
    "2077-0383"
  ],
  "landing_url": "https://europepmc.org/article/MED/42881823",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2705|Atrial Fibrillation Management and Outcomes"
    ]
  ],
  "openalex": "W7214099630",
  "pdf_url": "https://europepmc.org/articles/PMC13665372?pdf=render",
  "pmcid": "PMC13665372",
  "pmid": "42881823",
  "published": "2026-09-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/8pd8a158cwekz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:16Z",
      "native_id": "MED:42881823",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42881823"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Atrial Fibrillation Management and Outcomes",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Cardiac CT Roadmap for Left Atrial Appendage Occlusion: From Planning to Strategy to Follow-Up.",
  "title_text": "Cardiac CT Roadmap for Left Atrial Appendage Occlusion: From Planning to Strategy to Follow-Up.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:16Z",
  "url": "https://research.draconitic.com/paper/8pd8a158cwekz",
  "venue": "Journal of clinical medicine",
  "versions": []
}