{
  "abstract": "Microbial communities underpin ocean productivity and biogeochemistry, but their functional adaptation to environmental gradients remains poorly understood. Codon usage bias (CUB), a marker of translational efficiency, constrains growth rate potential, yet its role in functional adaptation across natural communities is underexplored. By analysing 589 metagenome-derived microbial communities from the global ocean, we demonstrate that CUB in 320 metabolism-related gene groups capture genomic adaptation to distinct temperature and nutrient concentrations. We identified four adaptation signatures shaped by distinct temperature-nutrient regimes, revealing how microbes optimize protein synthesis in their ecological niche. This genome-centric approach deepens our understanding of functional adaptation in uncultured marine microbes and provides a framework to inform ocean biogeochemical models and predict microbial responses to climate-driven changes.",
  "abstract_shown": true,
  "affiliations": [
    "Nantes Universite, Ecole Centrale Nantes, CNRS, LS2N, UMR 6004"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "C. G. Gouzien"
    },
    {
      "name": "A. Bagnaro"
    },
    {
      "name": "L. Garczarek"
    },
    {
      "name": "M. Ardyna"
    },
    {
      "name": "F. Joux"
    },
    {
      "affs": [
        0
      ],
      "name": "S. Chaffron"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8qynpv3k4wfyk.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.02.755941",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.10.02.755941v1.full",
  "id": "8qynpv3k4wfyk",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.10.02.755941v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "microbiology"
    ],
    [
      "openalex",
      "1312|RNA and protein synthesis mechanisms"
    ]
  ],
  "openalex": "W7216175798",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.10.02.755941v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-02",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/8qynpv3k4wfyk.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:25:55Z",
      "native_id": "10.64898/2026.10.02.755941",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.10.02.755941v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:microbiology",
      "subfield": "microbiology"
    }
  ],
  "title": "Codon usage bias maps ocean microbiome adaptation to temperature-nutrients regimes",
  "title_text": "Codon usage bias maps ocean microbiome adaptation to temperature-nutrients regimes",
  "type": "preprint",
  "updated_at": "2026-10-30T12:25:55Z",
  "url": "https://research.draconitic.com/paper/8qynpv3k4wfyk",
  "venue": "bioRxiv",
  "versions": []
}