{
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  "affiliations": [
    "Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhang Jiang Hi-Tech Park, Pudong, Shanghai, China, 201203",
    "University of Chinese Academy of Sciences, No. 19AYuquan Road, Beijing, China, 100049",
    "College of Pharmacy, Nanjing University of Chinese Medicine, No.138 Xianlin Avenue, Qixia District, Nanjing, Jiangsu, China, 210023",
    "School of Pharmaceutical Engineering",
    "Shenyang Pharmaceutical University",
    "Alphama Biotechnology Suzhou Co., Ltd.",
    "State Key Laboratory of Green Chemical Synthesis and Conversion, College of Pharmaceutical Sciences and Institute of Pharmaceutical Science and Technology",
    "Zhejiang University of Technology",
    "Key Laboratory for Green Pharmaceutical Technology and Equipment",
    "Zhejiang University of Technology) of Ministry of Education, and Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs"
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      "name": "Hanqi Du"
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      "name": "Weiwei Lu"
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    {
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      "name": "Yujun Zhao"
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    {
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      "name": "Xuan Wang",
      "orcid": "0000-0003-4986-0231"
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    {
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      "name": "Xiaojie Lu"
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  "bibtex": "https://research.draconitic.com/paper/8r24af9ajgaqp.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15011669/v1",
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  "id": "8r24af9ajgaqp",
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  "published": "2026-11-04",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/8r24af9ajgaqp.ris",
  "sources": [
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  "subjects": [
    {
      "field": "chemistry",
      "origin": "source:chemrxiv",
      "subfield": "general"
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  ],
  "title": "DEL-Flow: AI-Driven Structural Generation and Activity Validation of MDM2-Targeting Macrocyclic Peptides",
  "title_text": "DEL-Flow: AI-Driven Structural Generation and Activity Validation of MDM2-Targeting Macrocyclic Peptides",
  "type": "preprint",
  "updated_at": "2026-11-06T00:20:51Z",
  "url": "https://research.draconitic.com/paper/8r24af9ajgaqp",
  "venue": "ChemRxiv",
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}