{
  "abstract": "椎间盘是人体最大的无血管组织，椎间盘软骨终板代谢失衡、髓核与纤维环营养能量交换受阻，是椎间盘退变（IVDD）进展加速的核心病理机制。近年来研究证实，葡萄糖代谢的作用远不止能量供应，其代谢过程中的关键酶、代谢产物及膜转运蛋白，可通过细胞蛋白翻译后修饰、细胞周期耦合、机械信号感知等多维度调控细胞命运。随着椎间盘退变病理机制研究的不断深入，葡萄糖转运体蛋白（GLUTs）被证实是调控椎间盘营养交换与代谢稳态的关键因子，靶向干预 GLUTs 具有成为椎间盘退变治疗靶点的潜在价值。据此，本文围绕 GLUTs 在椎间盘退变中的代谢调控机制展开综述，旨在为推进 GLUTs 作为椎间盘退变靶向治疗的研究提供理论支撑。",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "武敬盛"
    },
    {
      "name": "彭国璇"
    },
    {
      "name": "黄明智"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8v5pjsp7hgryr.bib",
  "cited_by": 0,
  "doi": null,
  "fulltext_url": "http://zszd.publish.founderss.cn/thesisDetails#10.3969/j.issn.1007-4287.2026.10.022",
  "id": "8v5pjsp7hgryr",
  "issns": [
    "1007-4287"
  ],
  "landing_url": "http://zszd.publish.founderss.cn/thesisDetails#10.3969/j.issn.1007-4287.2026.10.022",
  "language": "zh",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RB1-214"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-24",
  "publisher": "Editorial Office of Chinese Journal of Laboratory Diagnosis",
  "ris": "https://research.draconitic.com/paper/8v5pjsp7hgryr.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:47Z",
      "native_id": "b5fdc977e2534664b568213f8e749b7e",
      "source": "doaj",
      "url": "http://zszd.publish.founderss.cn/thesisDetails#10.3969/j.issn.1007-4287.2026.10.022"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RB1-214",
      "subfield": "general"
    }
  ],
  "title": "葡萄糖转运体在椎间盘退变中的代谢调控研究进展",
  "title_text": "葡萄糖转运体在椎间盘退变中的代谢调控研究进展",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:44:47Z",
  "url": "https://research.draconitic.com/paper/8v5pjsp7hgryr",
  "venue": "Zhongguo shiyan zhenduanxue",
  "versions": []
}