{
  "abstract": "Objective: To identify risk factors for flexible gastrointestinal endoscope reprocessing failure and develop a practical risk-scoring model for the early identification of high-risk reprocessing cycles.\n\nMethods: This retrospective observational study, conducted from January to December 2025 at three endoscopy centers, included 2744 reprocessing cycles that adhered to WS 507-2016. Internal validation was performed using a split-sample approach, with 70% of the sample used for model derivation and 30% for validation. Predictors were selected using univariable and multivariable logistic regression and converted into an integer-based scoring system, with the optimal cutoff determined using the Youden index. Reporting followed the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis and Strengthening the Reporting of Observational Studies in Epidemiology guidelines, and the study was conducted in accordance with the Declaration of Helsinki.\n\nResults: Among the 2744 eligible reprocessing cycles, 682 (24.85%) exhibited reprocessing failure. Six independent predictors were identified: brushing personnel, washer–disinfector type, accessory use frequency, prior repair history, time from removal to reprocessing, and staff age. The scoring system, with a range of −2 to 18, achieved an area under the curve of 0.834 (95% confidence interval: 0.804–0.864) in the validation cohort. At a cutoff of ≥10, sensitivity was 0.725, specificity was 0.808, positive predictive value was 0.554, and negative predictive value was 0.899. Calibration was satisfactory based on the Hosmer–Lemeshow test and bootstrap analysis.\n\nConclusions: The internally validated scoring system enables the early identification of high-risk reprocessing cycles and may support quality improvement efforts. However, external validation is needed to assess its generalizability.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine, China",
    "Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Liangyu Fang",
      "orcid": "0000-0002-4615-6524"
    },
    {
      "affs": [
        0
      ],
      "name": "Xiaoxuan Zhou"
    },
    {
      "affs": [
        0
      ],
      "name": "Meifeng Wu"
    },
    {
      "affs": [
        1
      ],
      "name": "Yinchuan Xu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8y0ptmf8b0f70.bib",
  "cited_by": 0,
  "doi": "10.1177/03000605261491484",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13735076/",
  "id": "8y0ptmf8b0f70",
  "issns": [
    "0300-0605",
    "1473-2300"
  ],
  "landing_url": "https://doi.org/10.1177/03000605261491484",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Observational Study"
    ],
    [
      "openalex",
      "2404|Medical Device Sterilization and Disinfection"
    ]
  ],
  "openalex": "W7214582777",
  "pdf_url": null,
  "pmcid": "PMC13735076",
  "pmid": "42803735",
  "published": "2026-09-28",
  "publisher": "SAGE Publications",
  "ris": "https://research.draconitic.com/paper/8y0ptmf8b0f70.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:20:51Z",
      "native_id": "PMC13735076",
      "source": "pmc",
      "url": "https://doi.org/10.1177/03000605261491484"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2404|Medical Device Sterilization and Disinfection",
      "subfield": "microbiology"
    }
  ],
  "title": "Development and internal validation of a risk-scoring model for gastrointestinal flexible endoscope reprocessing failure: A retrospective observational study",
  "title_text": "Development and internal validation of a risk-scoring model for gastrointestinal flexible endoscope reprocessing failure: A retrospective observational study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:20:51Z",
  "url": "https://research.draconitic.com/paper/8y0ptmf8b0f70",
  "venue": "The Journal of International Medical Research",
  "versions": []
}