{
  "abstract": "Recipients transplanted for bronchiectasis in the context of a primary immune deficiency, such as common variable immunodeficiency, are at a high risk of severe infection in post-transplantation leading to poorer long-term outcomes than other transplant indications. In this report, we present a fatal case due to chronic Pseudomonas aeruginosa bronchopulmonary infection in a lung transplant recipient with common variable immunodeficiency despite successful eradication of an extensively drug-resistant (XDR) strain with IgM/IgA-enriched immunoglobulins and bacteriophage therapy. The fatal evolution despite a drastic adaptation of the immunosuppressive regimen and the maximal antibiotic therapy strategy raises the question of the contraindication of lung transplantation in such a context of primary immunodeficiency. Keywords: primary immunodeficiency diseases, lung transplantation, Pseudomonas aeruginosa , phage therapy, immunoglobulin therapy",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Manon Levêque"
    },
    {
      "name": "Nadim Cassir"
    },
    {
      "name": "Fanny Mathias"
    },
    {
      "name": "Cindy Fevre"
    },
    {
      "name": "Florence Daviet"
    },
    {
      "name": "Julien Bermudez"
    },
    {
      "name": "Geoffrey Brioude"
    },
    {
      "name": "Florence Peyron"
    },
    {
      "name": "Martine Reynaud-Gaubert"
    },
    {
      "name": "Benjamin Coiffard"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/8y0y3ktxfpcd1.bib",
  "cited_by": 15,
  "doi": "10.2147/idr.s413900",
  "fulltext_url": null,
  "id": "8y0y3ktxfpcd1",
  "issns": [
    "1178-6973"
  ],
  "landing_url": "https://hal.science/hal-05795768v1",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2403|Immunodeficiency and Autoimmune Disorders"
    ]
  ],
  "openalex": "W4382601368",
  "pdf_url": "https://www.dovepress.com/getfile.php?fileID=90840",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-12",
  "publisher": "Dove Medical Press",
  "ris": "https://research.draconitic.com/paper/8y0y3ktxfpcd1.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:55Z",
      "native_id": "hal-05795768",
      "source": "hal",
      "url": "https://hal.science/hal-05795768v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2403|Immunodeficiency and Autoimmune Disorders",
      "subfield": "immunology"
    }
  ],
  "title": "Refractory Pseudomonas aeruginosa Bronchopulmonary Infection After Lung Transplantation for Common Variable Immunodeficiency Despite Maximal Treatment Including IgM/IgA-Enriched Immunoglobulins and Bacteriophage Therapy",
  "title_text": "Refractory Pseudomonas aeruginosa Bronchopulmonary Infection After Lung Transplantation for Common Variable Immunodeficiency Despite Maximal Treatment Including IgM/IgA-Enriched Immunoglobulins and Bacteriophage Therapy",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:55Z",
  "url": "https://research.draconitic.com/paper/8y0y3ktxfpcd1",
  "venue": "Infection and Drug Resistance",
  "versions": []
}