{
  "abstract": "INTRODUCTION: Primary tracheal schwannoma is an extremely rare benign tumor, and despite its typical slow growth, it can cause life-threatening airway obstruction as it enlarges. We report a case of an endotracheal schwannoma that exhibited rapid enlargement during the preoperative waiting period. The tumor was safely resected with veno-venous extracorporeal membrane oxygenation (V-V ECMO) support because of the risk of complete airway obstruction.\n\nCASE PRESENTATION: A 73-year-old woman presented with hemoptysis. CT revealed a broad-based endotracheal tumor measuring 11 × 9 × 14 mm that was located 30 mm proximal to the carina. Bronchoscopic biopsy suggested benign schwannoma. The patient returned with worsening dyspnea and increased cough 2 weeks later. Follow-up CT showed rapid enlargement of the tumor to 17 × 12 × 21 mm, leaving a residual airway diameter of 4.2 mm. Given the risk of ventilation failure during the induction of general anesthesia, V-V ECMO was established while the patient was awake under local anesthesia. After adequate extracorporeal gas exchange was confirmed, general anesthesia was induced, followed by orotracheal intubation. Through a median sternotomy, the cervical and upper mediastinal trachea was exposed. The tumor-bearing tracheal segment was circumferentially resected, and primary end-to-end anastomosis was performed. The postoperative course was uncomplicated, and the patient remained recurrence-free at 12 months after surgery.\n\nCONCLUSIONS: Although benign tracheal schwannomas are generally slow-growing, rapid enlargement can occur and potentially cause life-threatening airway obstruction. In patients with severe tracheal obstruction, planned establishment of V-V ECMO before induction of general anesthesia may provide an additional margin of safety during airway management and tracheal reconstruction.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Surgery, Division of General Thoracic Surgery and Breast and Endocrine Surgery, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan",
    "Department of Pathology, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ryota Yasuda"
    },
    {
      "affs": [
        0
      ],
      "name": "Yasuaki Kubouchi"
    },
    {
      "affs": [
        1
      ],
      "name": "Sachiko Yasuda"
    },
    {
      "affs": [
        1
      ],
      "name": "Hiroshi Ishii"
    },
    {
      "affs": [
        0
      ],
      "name": "So Futagoishi"
    },
    {
      "affs": [
        0
      ],
      "name": "Masaya Yamasaki"
    },
    {
      "affs": [
        0
      ],
      "name": "Yuji Nozaka"
    },
    {
      "affs": [
        0
      ],
      "name": "Wakako Fujiwara"
    },
    {
      "affs": [
        0
      ],
      "name": "Shinji Matsui"
    },
    {
      "affs": [
        0
      ],
      "name": "Yoshiteru Kidokoro"
    },
    {
      "affs": [
        0
      ],
      "name": "Yugo Tanaka"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/91hgzpn0zd2jw.bib",
  "cited_by": 0,
  "doi": "10.70352/scrj.cr.26-0686",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13720762/",
  "id": "91hgzpn0zd2jw",
  "issns": [
    "2198-7793"
  ],
  "landing_url": "https://doi.org/10.70352/scrj.cr.26-0686",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2728|Neurofibromatosis and Schwannoma Cases"
    ]
  ],
  "openalex": "W7223911765",
  "pdf_url": "https://www.jstage.jst.go.jp/article/scrj/12/1/12_cr.26-0686/_pdf",
  "pmcid": "PMC13720762",
  "pmid": "42964556",
  "published": "2026-10-28",
  "publisher": "Japan Surgical Society",
  "ris": "https://research.draconitic.com/paper/91hgzpn0zd2jw.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T12:21:35Z",
      "native_id": "PMC13720762",
      "source": "pmc",
      "url": "https://doi.org/10.70352/scrj.cr.26-0686"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Neurofibromatosis and Schwannoma Cases",
      "subfield": "neurology"
    }
  ],
  "title": "Surgical Resection of a Rapidly Enlarging Endotracheal Schwannoma under Veno-Venous Extracorporeal Membrane Oxygenation Support: A Case Report",
  "title_text": "Surgical Resection of a Rapidly Enlarging Endotracheal Schwannoma under Veno-Venous Extracorporeal Membrane Oxygenation Support: A Case Report",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:21:35Z",
  "url": "https://research.draconitic.com/paper/91hgzpn0zd2jw",
  "venue": "Surgical Case Reports",
  "versions": []
}