{
  "abstract": "Cronkhite-Canada syndrome (CCS) is a rare disorder characterized by gastrointestinal polyposis and ectodermal abnormalities. We report the case of a 64-year-old man with CCS complicated by primary cutaneous peripheral T-cell lymphoma (PC-PTCL) and membranous nephropathy. Cutaneous lymphoma was controlled using topical corticosteroids and phototherapy. During the clinical course of CCS, the patient developed proteinuria, and a renal biopsy revealed membranous nephropathy with equivocal phospholipase A2 receptor staining. Corticosteroid therapy improved both the gastrointestinal manifestations and proteinuria. This case suggests a possible immune-mediated association among CCS, PC-PTCL, and membranous nephropathy.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "name": "Kohei Kiso"
    },
    {
      "name": "Yusuke Shimoyama"
    },
    {
      "name": "Saki Okuda-Hiwatashi"
    },
    {
      "name": "Taku Fujimura"
    },
    {
      "name": "Yoshihide Asano"
    },
    {
      "name": "Rui Makino"
    },
    {
      "name": "Tetsuhiro Tanaka"
    },
    {
      "name": "Hideya Iwaki"
    },
    {
      "name": "Daisuke Okamoto"
    },
    {
      "name": "Hiroshi Nagai"
    },
    {
      "name": "Takeo Naito"
    },
    {
      "name": "Rintaro Moroi"
    },
    {
      "name": "Yoichi Kakuta"
    },
    {
      "name": "Atsushi Masamune"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/92pmak5ksjr1q.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.7143-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7143-26/_article",
  "id": "92pmak5ksjr1q",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7143-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2734|Genetic factors in colorectal cancer"
    ]
  ],
  "openalex": "W7213895156",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7143-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/92pmak5ksjr1q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.7143-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7143-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2734|Genetic factors in colorectal cancer",
      "subfield": "general"
    }
  ],
  "title": "Cronkhite-Canada Syndrome Associated with Primary Cutaneous Peripheral T-cell Lymphoma and Membranous Nephropathy: A Case Report",
  "title_text": "Cronkhite-Canada Syndrome Associated with Primary Cutaneous Peripheral T-cell Lymphoma and Membranous Nephropathy: A Case Report",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/92pmak5ksjr1q",
  "venue": "Internal Medicine",
  "versions": []
}