{
  "abstract": "Many partial volume correction approaches make use of anatomical information, readily available in PET/MRI systems but it is not clear what approach is best. Seven novel approaches to partial volume correction were evaluated, including several post-reconstruction methods and several reconstruction methods that incorporate anatomical information. These were compared with an MRI-independent approach (reblurred van Cittert ) and uncorrected data. Monte Carlo PET data were generated for activity distributions representing both 18F FDG and amyloid tracer uptake. Post-reconstruction methods provided the best recovery with ideal segmentation but were particularly sensitive to mis-registration. Alternative approaches performed better in maintaining lesion contrast (unseen in MRI) with good noise control. These were also relatively insensitive to mis-registration errors. The choice of method will depend on the specific application and reliability of segmentation and registration algorithms.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "B.F. Hutton"
    },
    {
      "name": "B.A. Thomas"
    },
    {
      "name": "K. Erlandsson"
    },
    {
      "name": "A. Bousse"
    },
    {
      "name": "A. Reilhac-Laborde"
    },
    {
      "name": "D. Kazantsev"
    },
    {
      "name": "S. Pedemonte"
    },
    {
      "name": "K. Vunckx"
    },
    {
      "name": "S.R. Arridge"
    },
    {
      "name": "S. Ourselin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/945efjn1yfmhz.bib",
  "cited_by": 44,
  "doi": "10.1016/j.nima.2012.07.059",
  "fulltext_url": null,
  "id": "945efjn1yfmhz",
  "issns": [
    "0168-9002",
    "1872-9576"
  ],
  "landing_url": "https://hal.science/hal-05763781v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.phys"
    ],
    [
      "hal",
      "1.phys.phys"
    ],
    [
      "hal",
      "2.phys.phys.phys-med-ph"
    ],
    [
      "openalex",
      "2741|Medical Imaging Techniques and Applications"
    ]
  ],
  "openalex": "W2020058592",
  "pdf_url": "https://www.sciencedirect.com/science/article/pii/S0168900212008558/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-25",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/945efjn1yfmhz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:40Z",
      "native_id": "hal-05763781",
      "source": "hal",
      "url": "https://hal.science/hal-05763781v1"
    }
  ],
  "subjects": [
    {
      "field": "physics",
      "origin": "hal:2.phys.phys.phys-med-ph",
      "subfield": "biological-medical"
    }
  ],
  "title": "What approach to brain partial volume correction is best for PET/MRI?",
  "title_text": "What approach to brain partial volume correction is best for PET/MRI?",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:40Z",
  "url": "https://research.draconitic.com/paper/945efjn1yfmhz",
  "venue": "Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment",
  "versions": []
}