{
  "abstract": "Background\n\nRight ventricular (RV) dysfunction is a known marker of adverse outcomes in acute pulmonary embolism (PE). However, the prognostic utility of individual echocardiographic parameters in clinically heterogeneous patient populations remains a matter of debate. This study aimed to evaluate the association of baseline echocardiographic parameters of RV dysfunction with the Pulmonary Embolism Severity Index (PESI) score and in-hospital mortality.Methods\n\nWe prospectively enrolled 32 consecutive patients with computed tomography-confirmed acute PE. A comprehensive transthoracic echocardiogram was performed within 12 hours of admission. Parameters including tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RV FAC), tricuspid annular systolic velocity (S'), and RV myocardial performance index (MPI) were measured. The PESI score was calculated for all patients. No a priori power calculation was performed, and analyses were exploratory; significance was judged against a Bonferroni-corrected threshold for the systolic parameters tested.Results\n\nThe mean age was 55.4 ± 18.0 years, and the mean PESI score was 115.2 ± 40.5, indicating a high-risk cohort (59.4% in PESI classes IV-V). In-hospital mortality was 12.5%. Baseline TAPSE, S', and RV FAC showed no significant correlation with the continuous PESI score (p = 0.084, p = 0.235, and p = 0.637, respectively) and no significant association with in-hospital mortality (p > 0.05 for all). Abnormal RV FAC (<35%) was associated with PESI class distribution (χ²(4) = 11.08, p = 0.026, Cramér's V = 0.59) but did not retain significance after correction for multiple testing.Conclusions\n\nIn this small, prospective cohort of patients with acute PE and a high burden of comorbidities, conventional echocardiographic parameters of RV systolic function, including TAPSE and S', were not significantly associated with the PESI score or in-hospital mortality, and the single positive association (RV FAC with PESI class) did not survive correction for multiple testing. Given the limited sample and few events, these exploratory findings are hypothesis-generating and are consistent with an adjunctive - rather than stand-alone - role for echocardiographic RV assessment in risk stratification.",
  "abstract_shown": true,
  "affiliations": [
    "Cardiology, Holy Family Hospital, New Delhi, IND.",
    "Cardiology, Artemis Hospitals, New Delhi, IND.",
    "Cardiology, Max Super Speciality Hospital, New Delhi, IND.",
    "Cardiology, Max Healthcare Institute Limited, New Delhi, IND.",
    "Internal Medicine, Centerpoint Medical Center, Independence, USA."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mohit Bhagwati"
    },
    {
      "affs": [
        1
      ],
      "name": "Rahul Mehrotra"
    },
    {
      "affs": [
        0
      ],
      "name": "Amitabh Yaduvanshi"
    },
    {
      "affs": [
        0
      ],
      "name": "Vikas Kataria"
    },
    {
      "affs": [
        2
      ],
      "name": "Mohan Bhargava"
    },
    {
      "affs": [
        3
      ],
      "name": "Kewal Kishan Talwar"
    },
    {
      "affs": [
        4
      ],
      "name": "Pankti Shah"
    },
    {
      "affs": [
        4
      ],
      "name": "Pratyush Kumar"
    },
    {
      "affs": [
        4
      ],
      "name": "Kumar Abhishek"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/94rsebka4419x.bib",
  "cited_by": 0,
  "doi": "10.7759/cureus.116990",
  "fulltext_url": "https://europepmc.org/articles/PMC13711138",
  "id": "94rsebka4419x",
  "issns": [
    "2168-8184"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948057",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Cardiology"
    ],
    [
      "heading",
      "Emergency Medicine"
    ],
    [
      "heading",
      "Pulmonology"
    ],
    [
      "openalex",
      "2724|Venous Thromboembolism Diagnosis and Management"
    ]
  ],
  "openalex": "W7214525523",
  "pdf_url": "https://europepmc.org/articles/PMC13711138?pdf=render",
  "pmcid": "PMC13711138",
  "pmid": "42948057",
  "published": "2026-09-27",
  "publisher": "Cureus Inc.",
  "ris": "https://research.draconitic.com/paper/94rsebka4419x.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:35Z",
      "native_id": "MED:42948057",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948057"
    },
    {
      "first_seen": "2026-10-31T12:21:58Z",
      "native_id": "PMC13711138",
      "source": "pmc",
      "url": "https://doi.org/10.7759/cureus.116990"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Cardiology",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Prognostic Value of Conventional Echocardiographic Parameters of Right Ventricular Dysfunction in a Real-World Cohort of Patients With Acute Pulmonary Embolism.",
  "title_text": "Prognostic Value of Conventional Echocardiographic Parameters of Right Ventricular Dysfunction in a Real-World Cohort of Patients With Acute Pulmonary Embolism.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:58Z",
  "url": "https://research.draconitic.com/paper/94rsebka4419x",
  "venue": "Cureus",
  "versions": []
}