{ "abstract": "Background\n\nCrush syndrome (CS) is a clinical condition associated with multisystem organ dysfunction that develops after traumatic rhabdomyolysis and primarily affects the kidneys. The aim of this study was to characterize the incidence, risk factors, and treatment patterns of acute kidney injury (AKI) in earthquake victims with CS, with a particular focus on renal replacement therapy (RRT) use and clinical outcomes.Methods\n\nIn this retrospective multicenter study, 247 adult patients with earthquake-related CS who were admitted to intensive care units (ICUs) in 22 hospitals after the Kahramanmaraş 2023 earthquakes were analyzed. Demographic data, injury patterns, laboratory parameters, treatment protocols, and outcomes were evaluated during the first 15 days following ICU admission.Results\n\nAKI developed in 78.5% (n=194) of patients, and RRT was required in 62.4% (n=121) of those with AKI. Multiple logistic regression analysis demonstrated that myoglobin and creatinine levels were associated with an elevated risk of developing AKI (odds ratio [OR]: 1.001; 95% confidence interval CI: 1.000-1.001 and OR: 1.735; 95% CI: 1.151-2.615, respectively). Similarly, creatinine level and reasons for ICU admission were identified as factors influencing RRT administration. (OR: 1.7; 95% CI: 1.28-2.15 and OR: 2.9; 95% CI: 1.26-6.90, respectively). The 30-day mortality rate was higher in patients with AKI than in those without AKI. Mortality rates were similar between patients with AKI who received RRT and those who did not.Conclusion\n\nThis study demonstrates the high incidence of AKI in earthquake-related CS, underscores the need for improved disaster preparedness with adequate dialysis capacity and early risk stratification using serum myoglobin and creatinine levels for optimal management.", "abstract_shown": true, "affiliations": [ "Department of Anesthesiology and Reanimation, Çukurova University Faculty of Medicine, Adana, Türkiye.", "Division of Intensive Care Unit, Department of Internal Medicine, Çukurova University Faculty of Medicine, Adana, Türkiye.", "Department of Intensive Care, Ministry of Health, Etlik City Hospital, Ankara, Türkiye.", "Department of Intensive Care, Seyhan City Hospital, Adana, Türkiye.", "Division of Medical Intensive Care Unit, Department of Internal Medicine, Adana City Hospital, Adana, Türkiye.", "Department of Anesthesiology and Reanimation, Adana City Hospital, Adana, Türkiye.", "Department of Intensive Care, Dr. Ersin Arslan Training and Research Hospital, Gaziantep, Türkiye.", "Department of Surgical Intensive Care, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.", "Department of Intensive Care, Şanlıurfa Training and Research Hospital, Şanlıurfa, Türkiye.", "Division of Intensive Care Unit, Department of Internal Medicine, Mersin City Hospital, Mersin, Türkiye.", "Department of Intensive Care, Aralık City Hospital, Gaziantep, Türkiye.", "Department of Intensive Care, University of Health Sciences, Gülhane Faculty of Medicine, İstanbul, Türkiye.", "Department of Anesthesiology and Reanimation, Antalya Training and Research Hospital, Antalya, Türkiye.", "Department of Intensive Care, Nevşehir City Hospital, Nevşehir, Türkiye.", "Department of Anesthesiology and Reanimation, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Türkiye.", "Department of Anesthesiology and Reanimation, Erciyes University Faculty of Medicine, Kayseri, Türkiye.", "Department of Intensive Care, Harran University Faculty of Medicine, Şanlıurfa, Türkiye.", "Department of Intensive Care, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Türkiye.", "Department of Intensive Care, Selçuk University Faculty of Medicine, Konya, Türkiye.", "Department of Intensive Care, Kayseri City Hospital, Kayseri, Türkiye.", "Department of Pulmonary Surgery, İstanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Türkiye.", "Department of Biostatistic, Çukurova University Faculty of Medicine, Adana, Türkiye." ], "article_type": "research article", "arxiv": null, "author_total": 33, "authors": [ { "affs": [ 0 ], "name": "Zehra Hatipoğlu" }, { "affs": [ 0 ], "name": "Ömer Doğan", "orcid": "0009-0003-5347-7718" }, { "affs": [ 0 ], "name": "Mehmet Gökhan Gök" }, { "affs": [ 1 ], "name": "Kaniye Aydın" }, { "affs": [ 0 ], "name": "Ersel Güleç" }, { "affs": [ 0 ], "name": "Mediha Türktan" }, { "affs": [ 0 ], "name": "Ferhat Çetinkaya" }, { "affs": [ 2 ], "name": "Eda Macit Aydın" }, { "affs": [ 2 ], "name": "Büşra Tezcan" }, { "affs": [ 2 ], "name": "Murat Sayın" }, { "affs": [ 3 ], "name": "Ahu Dudu Akarca" }, { "affs": [ 4 ], "name": "Didem Sözütek" }, { "affs": [ 5 ], "name": "Devrim Söğüt Akdağ" }, { "affs": [ 6 ], "name": "Sinem Bayrakçı" }, { "affs": [ 7 ], "name": "Nazire Ateş Ayhan" }, { "affs": [ 8 ], "name": "İlhan Asude Ağahan" }, { "affs": [ 9 ], "name": "Gamze Koçak" }, { "affs": [ 9 ], "name": "Nihal Deniz Bulut Yüksel" }, { "affs": [ 10 ], "name": "Deniz Yüksel" }, { "affs": [ 11 ], "name": "Ahmet Coşar" }, { "affs": [ 11 ], "name": "Hatice Yağmurdur" }, { "affs": [ 11 ], "name": "Tülay Tuncer Peker" }, { "affs": [ 12 ], "name": "Nilgün Kavrut Öztürk" }, { "affs": [ 13 ], "name": "Vecihe Bayrak" }, { "affs": [ 14 ], "name": "Sedat Kaya" }, { "affs": [ 15 ], "name": "Aliye Esmaoğlu" }, { "affs": [ 16 ], "name": "Nuray Altay" }, { "affs": [ 17 ], "name": "Serhat Atılgan" }, { "affs": [ 18 ], "name": "Yeşim Şerife Bayraktar" }, { "affs": [ 19 ], "name": "Hilal Sipahioğlu" }, { "affs": [ 20 ], "name": "Kamuran Uluç" }, { "affs": [ 21 ], "name": "Yusuf Kemal Arslan" }, { "affs": [ 0 ], "name": "Dilek Özcengiz" } ], "bibtex": "https://research.draconitic.com/paper/962c3n5cce1q1.bib", "cited_by": 0, "doi": "10.14744/tjtes.2026.66645", "fulltext_url": "https://europepmc.org/articles/PMC13678144", "id": "962c3n5cce1q1", "issns": [ "1306-696X", "1307-7945" ], "landing_url": "https://europepmc.org/article/MED/42841896", "language": "eng", "licence": "CC-BY-NC", "licence_label": "CC BY-NC", "licence_source": "article", "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/", "metadata_licence": null, "native_subjects": [ [ "openalex", "2746|Muscle and Compartmental Disorders" ] ], "openalex": "W7220727996", "pdf_url": "https://europepmc.org/articles/PMC13678144?pdf=render", "pmcid": "PMC13678144", "pmid": "42841896", "published": "2026-10-01", "publisher": null, "ris": "https://research.draconitic.com/paper/962c3n5cce1q1.ris", "sources": [ { "first_seen": "2026-10-30T12:18:10Z", "native_id": "MED:42841896", "source": "europepmc", "url": "https://europepmc.org/article/MED/42841896" } ], "subjects": [ { "field": "medicine", "origin": "openalex:2746|Muscle and Compartmental Disorders", "subfield": "surgery" } ], "title": "Management of renal failure in earthquake-related crush syndrome: Multicenter intensive care outcomes.", "title_text": "Management of renal failure in earthquake-related crush syndrome: Multicenter intensive care outcomes.", "type": "peer-reviewed", "updated_at": "2026-10-30T12:18:10Z", "url": "https://research.draconitic.com/paper/962c3n5cce1q1", "venue": "Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES", "versions": [] }