{
  "abstract": "Annona muricata is traditionally used in the treatment of various infectious and chronic non – communicable diseases. The antioxidant activity of the leaves of A.muricata was assessed using DPPH scavenging assay. The DPPH radical scavenging potential was compared with the proven antioxidant, ascorbic acid. The result of the study showed that methanolic leaf extract of Annona muricata exhibited the greatest antioxidant activity than the other three extracting solvents used. Six major phytochemicals present in A. muricata were taken from Dr. Duke’s Phytochemical and Ethnobotanical database and docked with Xanthine oxidase (XO) protein. Campesterol obtained the minimum binding energy value and hence maximum stability. The experimental results were in agreement with the docking results. Fifteen similar molecules of Campesterol were taken from PubChem and docked with XO which revealed that 2-methyltetracycloheptade-7-en-5-ol based scaffolds can act as potent XO inhibitors.",
  "abstract_shown": true,
  "affiliations": [
    "PG and Research Department of Chemistry, DST-FIST Supported Department",
    "Affiliated to University of Kerala",
    "Department of Chemistry",
    "Sree Narayana College"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Achutha A S",
      "orcid": "0009-0008-6650-0637"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Akshaya K Mohan"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Vidya Viswanath"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Pushpa V L"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/96w15qqk5hztn.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010470/v1",
  "fulltext_url": null,
  "id": "96w15qqk5hztn",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010470/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1303|Traditional and Medicinal Uses of Annonaceae"
    ]
  ],
  "openalex": "W7221823230",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010470/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-14",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/96w15qqk5hztn.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "10.26434/chemrxiv.15010470",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010470/v1"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1303|Traditional and Medicinal Uses of Annonaceae",
      "subfield": "general"
    }
  ],
  "title": "Investigating the Antioxidant Potential of Annona muricata Leaves- An in silico Assisted in vitro Approach",
  "title_text": "Investigating the Antioxidant Potential of Annona muricata Leaves- An in silico Assisted in vitro Approach",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/96w15qqk5hztn",
  "venue": "ChemRxiv",
  "versions": []
}