{
  "abstract": "This dataset comprises bulk RNA-sequencing data from bilateral hippocampi of six untreated, 10-week-old male mice: three heterozygous RORγt-transgenic mice and three wild-type littermates on a C57BL/6 background. Total RNA was extracted using TRIzol, and RNA integrity numbers ranged from 8.1 to 8.6. Ribosomal RNA-depleted, directional libraries were prepared from 500 ng of RNA per sample and sequenced on an Illumina NextSeq 500 with a 2 × 36-bp paired-end configuration. The received reads were 35 or 36 bases long. The 48 original compressed FASTQ files were consolidated into 12 files, preserving 83,357,563 read pairs and their pairing. Original mm10 count and RPKM matrices each contain 49,585 feature entries. An additional GRCm39 reanalysis using Ensembl release 116 provides gene-level fragment counts for 78,348 annotated features, coordinate-sorted alignments and sample-level exploratory analyses. FastQC and MultiQC reports describe raw-read quality, and principal component analysis summarizes variation across all six samples. Original sequencing data and expression matrices are deposited in NCBI Gene Expression Omnibus under accession GSE347403.",
  "abstract_shown": true,
  "affiliations": [
    "Laboratory of Anatomy and Neuroscience, Department of Biomedical Sciences, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Ibaraki, Japan.",
    "Master's Program in Frontier Medical Sciences, Degree Program of Comprehensive Human Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Ibaraki, Japan.",
    "Master's and Doctoral Programs in Neuroscience, Degree Programs in Comprehensive Human Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Ibaraki, Japan.",
    "College of Medicine, School of Medicine and Health Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Ibaraki, Japan."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Tetsuya Sasaki"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Sae Sanaka"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Kenyu Nakamura"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Suguru Iwata"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Momo Morikawa"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yosuke Takei"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/97zza29sd32z0.bib",
  "cited_by": 0,
  "doi": "10.1016/j.dib.2026.113361",
  "fulltext_url": "https://europepmc.org/articles/PMC13743875",
  "id": "97zza29sd32z0",
  "issns": [
    "2352-3409"
  ],
  "landing_url": "https://europepmc.org/article/MED/42999513",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1312|Single-cell and spatial transcriptomics"
    ]
  ],
  "openalex": "W7222809973",
  "pdf_url": "https://europepmc.org/articles/PMC13743875?pdf=render",
  "pmcid": "PMC13743875",
  "pmid": "42999513",
  "published": "2026-08-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/97zza29sd32z0.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:42Z",
      "native_id": "MED:42999513",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42999513"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Single-cell and spatial transcriptomics",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Bulk RNA sequencing dataset of hippocampi from RORγt transgenic mice and wild type littermates.",
  "title_text": "Bulk RNA sequencing dataset of hippocampi from RORγt transgenic mice and wild type littermates.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:42Z",
  "url": "https://research.draconitic.com/paper/97zza29sd32z0",
  "venue": "Data in brief",
  "versions": []
}