{
  "abstract": "Purpose\n\nThe purpose of this study was to evaluate the different retinal layers of the posterior pole protocol and peripapillary areas in optical coherence tomography (OCT) to identify significant changes attributable to Steinert disease.Methods\n\nWe analyzed 128 eyes of healthy control subjects and 79 eyes of patients with Steinert disease. We performed the posterior pole and Nsite analytics peripapillary protocols on all subjects and compared thicknesses in the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigment epithelium (RPE), and complete retina (RETINA).Results\n\nPatients with Steinert disease showed significant alterations in retinal layer thickness compared with age-matched controls. Overall, a generalized thickening of retinal layers was observed; significant thickening of the RNFL was also found in the temporal area of the optic nerve and in the papillomacular bundle, which comprises the retinal ganglion cell axons connecting the macula with the optic nerve.Conclusions\n\nSteinert disease is associated with retinal structural alterations in retinal layer structure, OCT may provide potential structural markers of retinal involvement in Steinert disease.",
  "abstract_shown": true,
  "affiliations": [
    "Miguel Servet Ophthalmology Research and Innovation Group (GIMSO), Aragon Institute for Health Research (IIS Aragón), University of Zaragoza, Zaragoza, Spain.",
    "Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain.",
    "Department of Neurology, Miguel Servet University Hospital, Zaragoza, Spain.",
    "Department of Computer Science, University of Zaragoza, Zaragoza, Spain.",
    "Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Beatriz Cordón"
    },
    {
      "affs": [
        2
      ],
      "name": "Beatriz Pardiñas"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Mónica Hernández"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "María Jesús Rodrigo"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Elvira Mayordomo"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Luis Emilio Pablo"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Elena García-Martin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/99n2rr9ndsnmm.bib",
  "cited_by": 0,
  "doi": "10.3389/fopht.2026.1959492",
  "fulltext_url": "https://europepmc.org/articles/PMC13682967",
  "id": "99n2rr9ndsnmm",
  "issns": [
    "2674-0826"
  ],
  "landing_url": "https://europepmc.org/article/MED/42908507",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2731|Glaucoma and retinal disorders"
    ]
  ],
  "openalex": "W7220868009",
  "pdf_url": "https://europepmc.org/articles/PMC13682967?pdf=render",
  "pmcid": "PMC13682967",
  "pmid": "42908507",
  "published": "2026-10-07",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/99n2rr9ndsnmm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42908507",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42908507"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2731|Glaucoma and retinal disorders",
      "subfield": "general"
    }
  ],
  "title": "Structural changes in the retinal layers of patients with Steinert disease.",
  "title_text": "Structural changes in the retinal layers of patients with Steinert disease.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/99n2rr9ndsnmm",
  "venue": "Frontiers in ophthalmology",
  "versions": []
}