{
  "abstract": "Purpose: This study aimed to compare perioperative results, postoperative anal function, quality of life (QoL), and long-term outcomes between conformal sphincter preservation operation (CSPO) and modified Bacon operation for ultralow rectal cancer.\n\nMethods: Patients with ultralow rectal cancer undergoing CSPO (n = 123) and modified Bacon (n = 109) were included from Changhai and Xiangya Hospital, respectively, between 2011 and 2020. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were used to balanced baseline characteristics. Anal function was evaluated with Wexner scores and low anterior resection syndrome (LARS) score, and visual analog scale (VAS) for satisfaction. QoL was evaluated via EORTC QLQ-C30 and QLQ-CR38 questionnaires.\n\nResults: After exclusions, 122 patients in the CSPO group and 108 in the modified Bacon group were analyzed. Following adjustment via PSM and IPTW, the CSPO group demonstrated a shorter operative time, postoperative hospital stay, flatus and defecation time, postoperative anal function recovery time, and better satisfaction with anal function compared to the modified Bacon group. Multivariable analysis showed that neoadjuvant radiotherapy (β=-1.184, 95% CI -1.95 to 0.42) and postoperative anal function recovery time (β=-0.184, 95% CI -0.25 to -0.12) significantly contributed to lower satisfaction with anal function.\n\nConclusion: This retrospective, observational, multicenter study compared CSPO with the modified Bacon for ultralow rectal cancer. Both approaches demonstrated comparable clinical efficacy, functional outcomes, and QoL. However, CSPO showed potential advantages in perioperative recovery, postoperative anal functional recovery, and patient-reported anal function satisfaction. These findings require confirmation in prospective studies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of General Surgery, School of Medicine, Yangpu Hospital, Tongji University, 450 Tengyue Road, Shanghai, 200090 China",
    "Department of Colorectal Surgery, Xiangya Hospital, Central South University, Changsha, 410008 China",
    "Department of Colorectal Surgery, Changhai Hospital, Naval Military Medical University, Shanghai, 200433 China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Haibo Ding"
    },
    {
      "affs": [
        1
      ],
      "name": "Binwen Yuan"
    },
    {
      "affs": [
        2
      ],
      "name": "Ge Sun"
    },
    {
      "affs": [
        2
      ],
      "name": "Guanyu Yu"
    },
    {
      "affs": [
        2
      ],
      "name": "Haifeng Gong"
    },
    {
      "affs": [
        2
      ],
      "name": "Xiaoming Zhu"
    },
    {
      "affs": [
        1
      ],
      "name": "Zhi Yang"
    },
    {
      "affs": [
        1
      ],
      "name": "Peng Zha"
    },
    {
      "affs": [
        2
      ],
      "name": "Xianhua Gao"
    },
    {
      "affs": [
        2
      ],
      "name": "Zheng Lou"
    },
    {
      "affs": [
        1
      ],
      "name": "Jian Li"
    },
    {
      "affs": [
        2
      ],
      "name": "Wei Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/99v1ag6degmm2.bib",
  "cited_by": 0,
  "doi": "10.1186/s12876-026-05206-5",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13741773/",
  "id": "99v1ag6degmm2",
  "issns": [
    "1471-230X"
  ],
  "landing_url": "https://doi.org/10.1186/s12876-026-05206-5",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2730|Colorectal Cancer Surgical Treatments"
    ]
  ],
  "openalex": "W7202098420",
  "pdf_url": null,
  "pmcid": "PMC13741773",
  "pmid": "42989124",
  "published": "2026-08-10",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/99v1ag6degmm2.ris",
  "sources": [
    {
      "first_seen": "2026-11-10T12:22:46Z",
      "native_id": "PMC13741773",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s12876-026-05206-5"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Colorectal Cancer Surgical Treatments",
      "subfield": "oncology"
    }
  ],
  "title": "Conformal sphincter preservation operation versus modified Bacon operation for ultralow rectal cancer: a multicenter retrospective study using propensity-score matching and inverse probability of treatment weighting",
  "title_text": "Conformal sphincter preservation operation versus modified Bacon operation for ultralow rectal cancer: a multicenter retrospective study using propensity-score matching and inverse probability of treatment weighting",
  "type": "peer-reviewed",
  "updated_at": "2026-11-10T12:22:46Z",
  "url": "https://research.draconitic.com/paper/99v1ag6degmm2",
  "venue": "BMC Gastroenterology",
  "versions": []
}