{
  "abstract": "Optimal models of rehabilitation dedicated for patients with heart failure (HF) remain under investigation. The aim of this study was to assess the safety and effectiveness of a 6-month home-based rehabilitation program in patients with HF. 63 patients with stable HF were randomized, 28 patients from intervention group completed the study and were included in the analysis. Assessments including the 6-minute walk test, respiratory muscle strength, and quality of life measures (SF-36 and Fatigue Severity Scale - FSS) were conducted at baseline and after 6 months. Additionally, adverse events and adherence to the training protocol were monitored. Due to objective challenges caused by the COVID-19 pandemic outbreak, the course and final outcomes of the study differed from the original protocol; the control group was not assessed after 6 months. In the intervention group, 6 months of rehabilitation resulted in statistically significant improvements: the 6-minute walk distance increased by 37.86 meters (p = 0.001), maximal inspiratory pressure (PImax) improved by 20.21 cmH₂O, and maximal expiratory pressure (PEmax) by 20.75 cmH₂O (both p < 0.01). A significant reduction in fatigue was observed, as measured by FSS, with a mean decrease of 0.68 points (p = 0.029). Adherence to the exercise protocol averaged 91.5 ± 15.3%. No serious adverse events were reported. The home-based rehabilitation program, including respiratory muscle training, is safe and effective for patients with chronic HF. It improves functional capacity and reduces fatigue levels. https://clinicaltrials.gov/ct2/show/NCT03780803, ClinicalTrials.gov, NCT03780803. Registered 19/12/2018.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Rehabilitation, Medical University of Bialystok, Bialystok, Poland.",
    "Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.",
    "Department of Cardiology and Internal Medicine with Cardiac Intensive Care Unit, Medical University of Bialystok, Bialystok, Poland."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mariusz Ciołkiewicz"
    },
    {
      "affs": [
        0
      ],
      "name": "Mariusz Wojciuk"
    },
    {
      "affs": [
        0
      ],
      "name": "Anna Kuryliszyn-Moskal"
    },
    {
      "affs": [
        0
      ],
      "name": "Agnieszka Dakowicz"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Emilia Sawicka-Śmiarowska"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Karol Kamiński"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9aza11ampd8e7.bib",
  "cited_by": 0,
  "doi": "10.3389/fresc.2026.1958027",
  "fulltext_url": "https://europepmc.org/articles/PMC13713856",
  "id": "9aza11ampd8e7",
  "issns": [
    "2673-6861"
  ],
  "landing_url": "https://europepmc.org/article/MED/42952845",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Clinical Trial"
    ],
    [
      "openalex",
      "2707|Cardiovascular and exercise physiology"
    ]
  ],
  "openalex": "W7221757549",
  "pdf_url": "https://europepmc.org/articles/PMC13713856?pdf=render",
  "pmcid": "PMC13713856",
  "pmid": "42952845",
  "published": "2026-10-14",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/9aza11ampd8e7.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:41Z",
      "native_id": "MED:42952845",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42952845"
    },
    {
      "first_seen": "2026-11-01T12:21:27Z",
      "native_id": "PMC13713856",
      "source": "pmc",
      "url": "https://doi.org/10.3389/fresc.2026.1958027"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2707|Cardiovascular and exercise physiology",
      "subfield": "general"
    }
  ],
  "title": "Beyond the clinic: a six-month home-based exercise and respiratory rehabilitation program improves functional capacity, respiratory muscle strength, and fatigue in chronic heart failure.",
  "title_text": "Beyond the clinic: a six-month home-based exercise and respiratory rehabilitation program improves functional capacity, respiratory muscle strength, and fatigue in chronic heart failure.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:21:27Z",
  "url": "https://research.draconitic.com/paper/9aza11ampd8e7",
  "venue": "Frontiers in rehabilitation sciences",
  "versions": []
}