{
  "abstract": "Background\n\nThis study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support.Methods and results\n\nWe retrospectively analysed data from adult patients who received VA-ECMO for cardiogenic shock after CABG at our centre between 2014 and 2025. Among the 10,256 patients who underwent CABG, 74 received ECMO postoperatively. Among these, 33 patients (44.6%) died during ECMO support, 15 patients (20.3%) died after ECMO removal, and 26 patients (35.1%) survived to hospital discharge. For distinguishing hospital mortality, the lactate level at 24 h after ECMO initiation (LAC-T24) (> 4.35 mmol/L, AUROC: 0.916) performed the best, followed by the lactate clearance at 24 h (LC-T24) (< 55.73%, AUROC: 0.915). Other predictive factors included CKMB activity at 24 h (CKMB-T24) (> 157 U/L; AUROC: 0.848), mean arterial pressure at 24 h (MAP-T24) (< 77.5 mmHg; AUROC: 0.844), SOFA-2 scores (> 11.5; AUROC: 0.835), and the pre-ECMO Sequential Organ Failure Assessment scores (SOFA-1) (> 10.5; AUROC: 0.815). The best model revealed the pre-ECMO updated SOFA-2 scores (P < 0.001) (OR: 1.793, 95% CI: 1.029-3.124, P = 0.039), LAC-T24 (OR: 1.395, 95% CI: 1.045-1.861, P = 0.024), CKMB-T24 (OR: 1.015, 95% CI: 1.003-1.026, P = 0.013), and MAP-T24 (OR: 0.895, 95% CI: 0.809-0.989, P = 0.029) as independent predictors of hospital mortality after VA-ECMO.Conclusion\n\nIn patients receiving ECMO treatment after CABG, in-hospital mortality rates remains high. In this study, LAC-T24, LC-T24, CKMB-T24, pre-ECMO SOFA-1 and SOFA-2 scores were identified as predictors of mortality.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Cardiovascular Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Erqi District, Zhengzhou, Henan, China.",
    "Department of Cardiovascular Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Erqi District, Zhengzhou, Henan, China. fugwei@163.com.",
    "Department of Cardiovascular Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Erqi District, Zhengzhou, Henan, China. 13783621195@163.com."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Chi Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Chencan Feng"
    },
    {
      "affs": [
        0
      ],
      "name": "Peng Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Yabai Kan"
    },
    {
      "affs": [
        0
      ],
      "name": "Ankang Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Xiaohu Li"
    },
    {
      "affs": [
        0
      ],
      "name": "Jing Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Chuang Liu"
    },
    {
      "affs": [
        1
      ],
      "name": "Guowei Fu"
    },
    {
      "affs": [
        2
      ],
      "name": "Hui Zhao"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9bacnvzn7teb4.bib",
  "cited_by": 0,
  "doi": "10.1186/s13019-026-04480-4",
  "fulltext_url": "https://europepmc.org/articles/PMC13721614",
  "id": "9bacnvzn7teb4",
  "issns": [
    "1749-8090"
  ],
  "landing_url": "https://europepmc.org/article/MED/42958294",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2204|Mechanical Circulatory Support Devices"
    ]
  ],
  "openalex": "W7171135024",
  "pdf_url": "https://europepmc.org/articles/PMC13721614?pdf=render",
  "pmcid": "PMC13721614",
  "pmid": "42958294",
  "published": "2026-07-25",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/9bacnvzn7teb4.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T00:20:48Z",
      "native_id": "MED:42958294",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42958294"
    },
    {
      "first_seen": "2026-11-03T12:22:16Z",
      "native_id": "PMC13721614",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s13019-026-04480-4"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study.",
  "title_text": "Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:16Z",
  "url": "https://research.draconitic.com/paper/9bacnvzn7teb4",
  "venue": "Journal of cardiothoracic surgery",
  "versions": []
}