{
  "abstract": "Metastatic tumors evade not only adaptive but also innate immune control. In a recent paper published in China Science Life Sciences, Jin and colleagues identify EID1 as a transcriptional and functional brake shared by dendritic cells (DCs) and natural killer (NK) cells. Genetic or nanoparticle-mediated EID1 inhibition strengthens DC-NK apposition, augments FPR1-dependent type I and II interferon responses through a mechanism involving FPR1 and potentially NK cell-derived ANXA1, and suppresses experimental metastatic colonization/outgrowth. The work connects a transcriptional-corepressor to innate immunosurveillance and suggests that the previously described ANXA1-FPR1 danger-sensing module may operate not only between dying cancer cells and DCs in primary sites, but also among NK cells and DCs at metastatic lesions.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "name": "Oliver Kepp"
    },
    {
      "name": "Guido Kroemer"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9c3w69tpxj1wy.bib",
  "cited_by": 0,
  "doi": "10.1007/s44466-026-00060-2",
  "fulltext_url": null,
  "id": "9c3w69tpxj1wy",
  "issns": [
    "3059-4774",
    "3059-4774"
  ],
  "landing_url": "https://hal.science/hal-05801093v1",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2403|Immune Cell Function and Interaction"
    ]
  ],
  "openalex": "W7214113699",
  "pdf_url": "https://hal.science/hal-05801093/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-23",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9c3w69tpxj1wy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:57Z",
      "native_id": "hal-05801093",
      "source": "hal",
      "url": "https://hal.science/hal-05801093v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2403|Immune Cell Function and Interaction",
      "subfield": "immunology"
    }
  ],
  "title": "Disinhibiting dendritic cell-natural killer cell cooperation against metastasis",
  "title_text": "Disinhibiting dendritic cell-natural killer cell cooperation against metastasis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:57Z",
  "url": "https://research.draconitic.com/paper/9c3w69tpxj1wy",
  "venue": "Immunity & Inflammation",
  "versions": []
}