{
  "abstract": "• PQEVs preparation was improved via enzymatic hydrolysis. • PQEVs were rich in immune-active components. • PQEVs acted via the NOD2/RIP2-MAPK/NF-κB pathway. • Plant cell culture enabled scalable PQEVs biomanufacturing.",
  "abstract_shown": true,
  "affiliations": [
    "Biotechnological Institute of Chinese Materia Medica, College of Pharmacy, Jinan University, Guangzhou, 511443, China.",
    "Shandong Provincial Key Laboratory of Carbohydrate and Glycoconjugate Drugs, Shandong Academy of Pharmaceutical Sciences, Jinan, 250101, China."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Jixu Wu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yu Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Jinghong Xu"
    },
    {
      "affs": [
        0
      ],
      "name": "Lin Dong"
    },
    {
      "affs": [
        1
      ],
      "name": "Xiuhua Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Weijuan Huang"
    },
    {
      "affs": [
        0
      ],
      "name": "Liyan Song"
    },
    {
      "affs": [
        0
      ],
      "name": "Rongmin Yu"
    },
    {
      "affs": [
        1
      ],
      "name": "Fei Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Jianhua Zhu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/9cjkre1zqeq44.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jpha.2026.101695",
  "fulltext_url": "https://europepmc.org/articles/PMC13742472",
  "id": "9cjkre1zqeq44",
  "issns": [
    "2095-1779",
    "2214-0883"
  ],
  "landing_url": "https://europepmc.org/article/MED/42997589",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1312|Extracellular vesicles in disease"
    ]
  ],
  "openalex": "W7163526620",
  "pdf_url": "https://europepmc.org/articles/PMC13742472?pdf=render",
  "pmcid": "PMC13742472",
  "pmid": "42997589",
  "published": "2026-06-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/9cjkre1zqeq44.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:42Z",
      "native_id": "MED:42997589",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42997589"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Extracellular vesicles in disease",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Panax quinquefolius derived extracellular vesicles promote post-chemotherapy immune reconstitution through the remodeling functions of macrophages via the NOD2/RIP2 axis.",
  "title_text": "Panax quinquefolius derived extracellular vesicles promote post-chemotherapy immune reconstitution through the remodeling functions of macrophages via the NOD2/RIP2 axis.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:42Z",
  "url": "https://research.draconitic.com/paper/9cjkre1zqeq44",
  "venue": "Journal of pharmaceutical analysis",
  "versions": []
}